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Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study

This study has been completed.
Sponsor:
Information provided by:
McGill University Health Center
ClinicalTrials.gov Identifier:
NCT00609427
First received: January 24, 2008
Last updated: June 1, 2010
Last verified: June 2010
History of Changes
  Purpose

The purpose of this study is to evaluate the effects of training in memory skills vs. use of external memory aids on everyday memory functioning in older people with mild cognitive impairment.


Condition Intervention Phase
Mild Cognitive Impairment
 Behavioral: MEMO programme (Inst Universitaire de Geriatrie, Montreal)
Behavioral: External memory aids training
 Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by McGill University Health Center:

Primary Outcome Measures:
  • Rey Auditory Verbal Learning Test [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
  • Wechsler Memory Scale - Logical Memory [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
  • Face-name associations test [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
  • Multifactorial Memory Questionnaire - Ability subscale [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Rivermead Behavioural Memory Test [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
  • FAS test (non-memory) [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
  • Category fluency (non-memory test) [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
  • Victoria Stroop Test (non-memory test) [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
  • Digit Span (non-memory test) [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]
  • Multifactorial Memory Questionnaire - Strategies and Contentment subscales [ Time Frame: 19-20 weeks ] [ Designated as safety issue: No ]

Estimated Enrollment: 30
Study Start Date: May 2008
Study Completion Date: May 2010
Primary Completion Date: May 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: EA
Training in external memory aids
 Behavioral: External memory aids training
8 weekly group sessions of training in the use of external memory aids, administered by clinical psychologist
Experimental: MT
Mnemonic training intervention
 Behavioral: MEMO programme (Inst Universitaire de Geriatrie, Montreal)
8 weekly group training sessions in mnemonic strategies, administered by clinical psychologist.
No Intervention: WL
Wait-list control

Detailed Description:

Some older people experience memory loss that is worse than other people of their age, although they are not demented. This condition is known as mild cognitive impairment (MCI). Healthy older people can learn mnemonic strategies to improve their memory abilities. Can cognitive rehabilitation help people with MCI do better on mental tasks or maintain better functioning in everyday life? This study will evaluate the effects of two different rehabilitation programmes. Patients in the memory training group will learn mental strategies aimed at improving memory. Patients in the memory compensation group will learn to use external memory aids.

  Eligibility

Ages Eligible for Study:   65 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Clinical diagnosis of mild cognitive impairment

Exclusion Criteria:

  • Unable to speak and understand English
  • Unable to comply with treatment program due to significant comorbid illness; OR
  • Anticipated inability to attend all study sessions
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00609427

Locations
Canada, Quebec
McGill University Health Centre
Montreal, Quebec, Canada, H3A 1A1
Sponsors and Collaborators
McGill University Health Center
Investigators
Principal Investigator: Lisa Koski, PhD Research Institute of the McGill University Health Centre
  More Information

No publications provided

Responsible Party: Lisa Koski, Research Institute of the McGill University Health Centre
ClinicalTrials.gov Identifier: NCT00609427     History of Changes
Other Study ID Numbers: PSY-07-015
Study First Received: January 24, 2008
Last Updated: June 1, 2010
Health Authority: Canada: Ethics Review Committee

Keywords provided by McGill University Health Center:
cognitive training
cognitive rehabilitation

Additional relevant MeSH terms:
Cognition Disorders
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on June 17, 2013