Language Function in Patients With Brain Tumors
The purpose of this study is to use an imaging method called functional magnetic resonance imaging (fMRI) in patients who have a tumor near an area of the brain that is believed to control language. The fMRI is a new kind of imaging that uses a strong magnetic field to look at functioning brain tissue. This kind of imaging will be used to study the effect of the brain tumor on your speech.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Reorganization of Language Function in Patients With Brain Tumors|
- To identify language organization prior to surgery in patients in whom a tumor invades or is directly adjacent to the expected location of one of the language centers. [ Time Frame: conclusion of study ] [ Designated as safety issue: No ]
- To assess language reorganization over time. [ Time Frame: conclusion of study ] [ Designated as safety issue: No ]
|Study Start Date:||May 2005|
|Study Completion Date:||March 2009|
|Primary Completion Date:||March 2009 (Final data collection date for primary outcome measure)|
Other: fMRI Scan, pre- and post language evaluation
All subjects will undergo functional MR imaging, pre- and post-surgical language evaluation, and electrocortical stimulation mapping. The brain tumor patients will undergo these procedures twice.
|United States, New York|
|Memorial Sloan Kettering Cancer Center|
|New York, New York, United States, 10065|
|Principal Investigator:||Andrei Holodny, MD||Memorial Sloan-Kettering Cancer Center|