Identification of Genetic, Biochemical and Hormonal Factors Contributing to Atrial Fibrillation
The purpose of this study is to establish a genebank repository of blood samples and data to generate information about the hereditary (genetic) basis of atrial fibrillation.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Identification of Genetic, Biochemical and Hormonal Factors Contributing to Atrial Fibrillation|
- Atrial fibrillation [ Time Frame: 4 years ] [ Designated as safety issue: No ]
- Stroke [ Time Frame: 4 years ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
plasma, serum, buffy coat, DNA
|Study Start Date:||August 2005|
|Estimated Study Completion Date:||June 2013|
|Estimated Primary Completion Date:||June 2013 (Final data collection date for primary outcome measure)|
Control subjects with no atrial fibrillation
Blood samples and data will be collected from subjects with atrial fibrillation and normal controls. The primary aim of future research using these samples is to identify mechanisms and pathogenesis of atrial fibrillation. Through this information, we hope to identify targets for new therapies and improve knowledge and understanding of atrial fibrillation. Identification of disease genes could improve strategies that prevent progression of atrial fibrillation to more persistent disease.