Assessment of a Teachable Moment for Smoking Cessation (TM)
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Purpose
A teachable moment (TM) refers to life events or transitions, such as physician visits, early detection screening feedback, pregnancy, and hospitalization for, and diagnosis of, disease, that inspire health behavior change. Despite strong intuitive appeal of the TM concept and over 150 studies of interventions implemented in a TM, there has been little investigation of the influence of TMs for smoking, particularly for promoting smoking cessation among those indirectly affected by a TM (e.g., relatives of cancer patients). This prospective observational study using a matched-group design will assess whether a lung cancer diagnosis increases enrollment in a smoking cessation program and cessation, and reduces smoking, among the patient's relatives/spouse who smoke. We will compare enrollment in a cessation program and cessation and smoking rates in 2 groups of smokers: 1) relatives/spouses of newly-diagnosed lung cancer patients, and 2) relatives/spouses of patients with an orthopedic condition. We will also explore mediators and moderators of a lung cancer diagnosis as a TM. This study could clarify the TM concept for smoking cessation, shed light on the underlying mechanisms of TMs, and guide future development and implementation of TM-based smoking cessation interventions.
| Condition | Intervention |
|---|---|
|
Nicotine Dependence |
Drug: Transdermal nicotine patch |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | Assessment of a Teachable Moment for Smoking Cessation |
- accrual rate [ Time Frame: one week ] [ Designated as safety issue: No ]
- smoking cessation rate [ Time Frame: one week ] [ Designated as safety issue: No ]
| Enrollment: | 234 |
| Study Start Date: | August 2007 |
| Study Completion Date: | February 2012 |
| Primary Completion Date: | December 2011 (Final data collection date for primary outcome measure) |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
1
Relatives of Cancer Patients
|
Drug: Transdermal nicotine patch
8 weeks; 4 weeks of 21mg, 2 weeks of 14mg, and 2 weeks of 7mg.
|
|
2
Relatives of Orthopedic Patients
|
Drug: Transdermal nicotine patch
8 weeks; 4 weeks of 21mg, 2 weeks of 14mg, and 2 weeks of 7mg.
|
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Probability Sample |
One group will be relatives/spouses of newly-diagnosed lung or head and neck cancer patients and the second group will be relatives/spouses of orthopedic patients. All participants will be regular smokers (i.e., smoke 10 cigarettes/day on average).
Inclusion Criteria:
- A relative (i.e., sibling, parent, child, grandparent, aunt, uncle, cousin) or spouse of a newly-diagnosed lung or head and neck cancer patient or orthopedic patient (e.g., arthritis, bone and joint infection, foot and ankle conditions, hand, wrist, and elbow conditions such as carpal tunnel syndrome, shoulder and elbow conditions, such as rotator cuff injury, and knee conditions, such as ligament damage repair);
- A regular smoker (i.e., smoke 10 cigarettes/day on average);
- Able to use NRT (see contraindications under Key Exclusion Criteria);
- Age 18 or older (to use NRT); and
- Living within ~50 miles of PENN (to allow for meetings at PENN).
Exclusion Criteria:
- Cannot communicate in English;
- Have current alcohol abuse/dependence;
- Are or have been diagnosed with cancer, asthma, HIV, emphysema, or COPD;
- Have a current medical problem for which NRT is contraindicated such as uncontrolled hypertension (> 150 over 90), unstable angina, heart attack or stroke within the past 6 months, and liver and/or kidney failure in the last 6-months;
- Currently use monoamine oxidase inhibitors or benzodiazepines, anti-psychotics, and antidepressants, including bupropion;
- Are allergic to adhesive tape or latex, and
- Are a female who is pregnant or nursing.
Contacts and Locations| United States, Pennsylvania | |
| University of Pennsylvania | |
| Philadelphia, Pennsylvania, United States, 19104 | |
| Principal Investigator: | Robert A Schnoll, PhD | University of Pennsylvania |
More Information
No publications provided
| Responsible Party: | Robert Schnoll, Associate Professor, University of Pennsylvania |
| ClinicalTrials.gov Identifier: | NCT00596440 History of Changes |
| Other Study ID Numbers: | 805712, NIH R01CA126969 |
| Study First Received: | January 8, 2008 |
| Last Updated: | January 14, 2013 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by University of Pennsylvania:
|
smoking teachable moment cancer |
Additional relevant MeSH terms:
|
Tobacco Use Disorder Smoking Substance-Related Disorders Mental Disorders Habits Nicotine Ganglionic Stimulants Autonomic Agents |
Peripheral Nervous System Agents Physiological Effects of Drugs Pharmacologic Actions Nicotinic Agonists Cholinergic Agonists Cholinergic Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action |
ClinicalTrials.gov processed this record on June 17, 2013