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Medical Office Intervention for Adolescent Drug Use - Attention Study Supplement

This study has been completed.
Sponsor:
Information provided by:
Children's Hospital Boston
ClinicalTrials.gov Identifier:
NCT00593034
First received: January 3, 2008
Last updated: March 7, 2011
Last verified: March 2011
History of Changes
  Purpose

This study will use the CCPT II to assess attention in 12-21 year olds enrolled in a randomized controlled trial of a brief behavioral treatment for substance abuse.

This study will describe at baseline levels of attention using a well validated instrument (Connors Continuous Performance Test II) and explore the association between attention levels and substance use. The primary study hypothesis is that lower initial levels of substance use (as measured by percent days abstinent) will be associated with higher attention levels. We envision that this data will inform a better understanding of how attention may modify treatment response.


Condition
Substance-related Disorders

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Medical Office Intervention for Adolescent Drug Use - Research Supplement for Under-represented Minorities

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Children's Hospital Boston:

Primary Outcome Measures:
  • Score on the Connors Continuous Performance Test II (CCPT II) [ Time Frame: Baseline ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Percentage of days abstinent [ Time Frame: 6 months ] [ Designated as safety issue: No ]

Enrollment: 42
Study Start Date: February 2007
Study Completion Date: February 2008
Primary Completion Date: February 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
Participants in this study will be 12-21 year old patients who have been referred to the Adolescent Substance Abuse Program for evaluation of drug or alcohol use and are participating in the parent study, "Medical Office Intervention for Adolescent Drug Abuse."

Detailed Description:

Research among adolescents with substance use problems presents unique challenges to investigators. Issues with recruitment, confidentiality, and follow-up have been cited as common limitations to research in this area. One likely contributor to decreased treatment persistence and follow-up is the limited ability to sustain attention that many adolescents, especially those with substance problems, may manifest. (Taper, 2002) Thus, assessing attention before beginning substance abuse treatment has the potential not only to inform the science of adolescent addiction medicine, but also to guide the development of therapies to specifically address attention deficits among adolescent substance users. Adolescent outpatients being treated for substance problems have not been systematically studied for clinical or subclinical attention levels.

The primary aims this study are as follows:

  1. To test the feasibility of administering the Connors Continuous Performance Test II (CCPT II), a well validated measure of attention, to a sample of 12-21 year old patients receiving treatment for substance abuse.
  2. To obtain baseline descriptive statistics on the CCPT II in a previously understudied group of young patients receiving treatment for substance abuse.
  3. To estimate the magnitude of the association between substance use and levels of attention at baseline before treatment.
  4. To explore the degree to which attention may affect response to substance abuse treatment in general and specifically motivational interviewing.
  Eligibility

Ages Eligible for Study:   12 Years to 21 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Participants in this study will be 12-21 year old patients who have been referred to the Adolescent Substance Abuse Program for evaluation of drug or alcohol use and are participating in the parent study, "Medical Office Intervention for Adolescent Drug Abuse."

Criteria

Inclusion Criteria:

  • CRAFFT score of 1 or more
  • Have used cannabis, alcohol or another drug on at least two occasions during the 30 days preceding their visit
  • Can read and understand English

Exclusion Criteria:

  • Require immediate hospitalization or referral to residential substance abuse treatment
  • Will not be available to complete the study assessments over the next 9 months.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00593034

Locations
United States, Massachusetts
Children's Hospital Boston
Boston, Massachusetts, United States, 02115
Sponsors and Collaborators
Children's Hospital Boston
Investigators
Principal Investigator: John R Knight, MD Children's Hospital Boston
  More Information

Additional Information:
Web site for the Center for Adolescent Substance Abuse Research, parent research group for the project.  This link exits the ClinicalTrials.gov site

Publications:

Responsible Party: John R. Knight, MD, Children's Hospital Boston
ClinicalTrials.gov Identifier: NCT00593034     History of Changes
Other Study ID Numbers: R01 DA014553-03S1
Study First Received: January 3, 2008
Last Updated: March 7, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by Children's Hospital Boston:
Alcohol abuse
Drug abuse

Additional relevant MeSH terms:
Substance-Related Disorders
Mental Disorders

ClinicalTrials.gov processed this record on June 18, 2013