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Ramanspectroscopy in Barrett's Esophagus

This study has been completed.
Sponsor:
Collaborator:
National Institutes of Health (NIH)
Information provided by:
Mayo Clinic
ClinicalTrials.gov Identifier:
NCT00588575
First received: December 22, 2007
Last updated: September 14, 2009
Last verified: September 2009
History of Changes
  Purpose

This study is being done to see if a new device, called near-infrared Raman spectroscopy, can provide similar information as that obtained from taking biopsies of the lining of your Barrett's esophagus


Condition
Barrett's Esophagus

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: In-Vivo Raman Spectroscopy of Barrett's Esophagus

Further study details as provided by Mayo Clinic:

Biospecimen Retention:   Samples Without DNA

esophageal biopsy


Enrollment: 119
Study Start Date: October 2004
Study Completion Date: October 2007
Primary Completion Date: May 2007 (Final data collection date for primary outcome measure)
Detailed Description:

In the search for means to enhance the surveillance of BE, optical spectroscopy is emerging as a candidate with high potential. Optical spectroscopic techniques measure specific light-tissue interactions, such as fluorescence, elastic scattering, and Raman (inelastic) scattering, which provide objective and quantitative diagnostic information about the molecular and/or structural status of tissue. Moreover, optical spectroscopy has the capacity to identify tissue pathology in situ in a rapid and non-destructive fashion. Among the optical spectroscopic techniques, near-infrared Raman spectroscopy (NIRS) is particularly promising because of the wealth of molecular-specific information contained in its spectra

  Eligibility

Ages Eligible for Study:   18 Years to 85 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Barrett's esophagus surveillance

Criteria

Inclusion Criteria:

  • Closed to further enrollment
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00588575

Locations
United States, Minnesota
Mayo Clinic
Rochester, Minnesota, United States, 55905
Sponsors and Collaborators
Mayo Clinic
National Institutes of Health (NIH)
Investigators
Principal Investigator: Louis M Wongkeesong, MD Mayo Clinic
  More Information

Additional Information:
Mayo Clinic Clinical Trials  This link exits the ClinicalTrials.gov site

No publications provided

Responsible Party: Louis Michel WongkeeSong, Mayo Clinic
ClinicalTrials.gov Identifier: NCT00588575     History of Changes
Other Study ID Numbers: 1999-04 00, DK67148, Raman
Study First Received: December 22, 2007
Last Updated: September 14, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by Mayo Clinic:
Barrett's Esophagus

Additional relevant MeSH terms:
Barrett Esophagus
Digestive System Abnormalities
Digestive System Diseases
Esophageal Diseases
Gastrointestinal Diseases

ClinicalTrials.gov processed this record on May 23, 2013