Aortic Distensibility (FAMRI)
Can software be developed to automatically aid in the measurement of abdominal aortic aneurysms, and is there a way to predict future rupture or growth of abdominal aortic aneurysms.
Abdominal Aortic Aneurysm
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||ECG-Gated Multidetector CT of Aortic Distensibility FAMRI|
- In year one, this data will be used to develop pulsatility software and test robustness. [ Time Frame: First Year ] [ Designated as safety issue: No ]
- In year two, the time-resolved CT angiographic datasets from each patient will be analyzed to determine peak AAA pulsatility and peak AAA relative pulsatility (to cross-sectional area within the aneurysm). [ Time Frame: Year Two ] [ Designated as safety issue: No ]
|Study Start Date:||November 2004|
|Study Completion Date:||July 2009|
|Primary Completion Date:||July 2009 (Final data collection date for primary outcome measure)|
Aortic aneurysm repair
Aortic aneurysm growth
Aortic aneurysm growth stable.
Hypothesis: ECG-gated multidetector CT and ECG-gated Dual Source CT can be used to create multiple volumetric datasets of the abdominal aorta over the time period of the cardiac cycle, allowing for direct and regional calculations of abdominal aortic distensibility over the entire volume of the abdominal aorta, providing insight into risk of abdominal aortic aneurysm rupture and early large vessel stiffness.
|United States, Minnesota|
|Rochester, Minnesota, United States, 55905|
|Principal Investigator:||Joel G. Fletcher, M.D.||Mayo Clinic Rochester Minnesota|