Trial record 1 of 1280 for:    aids and cancer and specimen
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AIDS and Cancer Specimen Bank (ACSB)

This study has been completed.
Sponsor:
Collaborators:
George Washington University
University of Hawaii
University of California, San Francisco
Kaiser Permanente
Information provided by:
Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier:
NCT00587912
First received: December 24, 2007
Last updated: April 20, 2011
Last verified: April 2011
  Purpose

The purpose of this study is to obtain clinical specimens from pathologists and physicians involved in the diagnosis and care of patients with AIDS and non-AIDS associated malignancies.

The National Cancer Institute has set up a Bank for tissues and biological fluids from HIVpositive and HIV-negative individuals in order to have specimens available for scientists studying malignancies associated with HIV disease.


Condition
Kaposi's Sarcoma AIDS Related
Kaposi's Sarcoma Classical
Non-Hodgkin's Lymphoma
HEMATOPOIETIC SYSTEM
Cancer
AIDS

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: AIDS and Cancer Specimen Bank (ACSB)

Resource links provided by NLM:


Further study details as provided by Memorial Sloan-Kettering Cancer Center:

Primary Outcome Measures:
  • Identify and improve access to tumor tissue, biological specimens, and associated clinical outcome data that could be utilized for research by the research community at-large on the pathogenesis of HIV and non-HIV associated malignancies. [ Time Frame: 3 years ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Blood, urine, other bodily fluids (eg, pleural fluid), and tumor tissue obtained from patients.


Enrollment: 65
Study Start Date: June 1997
Study Completion Date: April 2011
Primary Completion Date: April 2011 (Final data collection date for primary outcome measure)
Detailed Description:

The overall goal of the AIDS and Cancer Specimen Bank is to obtain clinical specimens from pathologists and physicians involved in the diagnosis and care of patients with AIDS and non- AIDS associated malignancies. These specimens will be banked and linked to a clinical data set so that experimental results obtained by analysis of specific specimens can be linked to relevant clinical data. Contents of the ACSB will be made available to researchers through an application to the National Cancer Institute. Strict patient confidentiality protection guidelines are in place for all specimens in the ACSB. The objective of this protocol is to obtain clinical specimens from potential participants in clinical trials conducted by the AIDS Malignancies Consortium, and from other patients with and without HIV infection, who have AIDS-Associated malignancies.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

The Source of specimens will include patients screened for participation on protocols conducted by the AIDS Malignancy Consortium, as well as other patients with HIV infection and cancer who are not eligible for participation in AMC trials, and patients without HIV who have malignancies associated with HIV or with immunosuppression.

Criteria

Inclusion Criteria:

  • Patient > 18 years of age
  • Suspected or confirmed AIDS-Associated malignancy with or without HIV infection
  • Will obtain fresh tissue and/or biological fluids
  • Patient signed the correct version of the informed consent

Exclusion Criteria:

  • N/A
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00587912

Locations
United States, New York
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10065
Sponsors and Collaborators
Memorial Sloan-Kettering Cancer Center
George Washington University
University of Hawaii
University of California, San Francisco
Kaiser Permanente
Investigators
Principal Investigator: David Straus, MD Memorial Sloan-Kettering Cancer Center
  More Information

Additional Information:
No publications provided

Responsible Party: David Straus, MD, Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier: NCT00587912     History of Changes
Other Study ID Numbers: 97-043
Study First Received: December 24, 2007
Last Updated: April 20, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by Memorial Sloan-Kettering Cancer Center:
Kaposi's Sarcoma AIDS Related
Kaposi's Sarcoma Classical
Non-Hodgkin's Lymphoma
HEMATOPOIETIC SYSTEM
Cancer
AIDS

Additional relevant MeSH terms:
AIDS-Related Opportunistic Infections
Neoplasms, Connective and Soft Tissue
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Vascular Tissue
HIV Infections
Sarcoma
Lymphoma, Non-Hodgkin
Sarcoma, Kaposi
Lymphoma
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
Herpesviridae Infections
DNA Virus Infections
Virus Diseases
Opportunistic Infections
Infection
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Parasitic Diseases
Immunologic Deficiency Syndromes

ClinicalTrials.gov processed this record on September 16, 2014