Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux
Investigation evaluating the effect of coffee on gastro-esophageal reflux disease.
|Study Design:||Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Supportive Care
|Official Title:||Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux|
- coffee leads to reflux events [ Time Frame: 48 hours ] [ Designated as safety issue: No ]
|Study Start Date:||May 2006|
|Study Completion Date:||January 2010|
|Primary Completion Date:||January 2010 (Final data collection date for primary outcome measure)|
Many patients with gastro-esophageal reflux disease (GERD) report that drinking coffee causes heartburn. The purpose of this study is to investigate the effects of coffee on gastro-esophageal acid reflux, and its relation to esophageal motility parameters in patients who are already scheduled to undergo 48 hour wireless pH testing as a result of having symptoms suggestive of GERD. The specific aims are to evaluate the effects of coffee on GERD during daily life and to elucidate the underlying pathogenic mechanism by which coffee induces reflux.
|United States, California|
|University of California Davis Medical Center|
|Sacramento, California, United States, 95817|
|Principal Investigator:||Peter Belafsky, MD, PhD||University of California, Davis|