Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules

This study has been completed.
Sponsor:
Collaborator:
Group Florence Nightingale
Information provided by (Responsible Party):
Ahmet Selcuk Can, Istanbul Science University
ClinicalTrials.gov Identifier:
NCT00571090
First received: December 10, 2007
Last updated: March 28, 2014
Last verified: March 2014
  Purpose

The aim of this study is to identify which ultrasonographic feature or a combination of features is the best predictor of thyroid cancer in thyroid nodules.


Condition Intervention
Thyroid Nodule
Procedure: Thyroid ultrasonography

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Evaluation of Thyroid Fine Needle Aspiration Biopsies: Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules

Resource links provided by NLM:


Further study details as provided by Istanbul Science University:

Primary Outcome Measures:
  • Thyroid cancer [ Time Frame: one year ] [ Designated as safety issue: No ]

Enrollment: 735
Study Start Date: June 2003
Study Completion Date: July 2013
Primary Completion Date: July 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Thyroid nodule
Subjects who present with thyroid nodules will be enrolled into the study. Euthyroid and hypothyroid subjects with a solitary thyroid nodule or multinodular goiter will be enrolled. For subjects with a suppressed TSH, a thyroid scan will be performed. Subjects with a hypoactive nodule in the thyroid scan and a low TSH will be enrolled.
Procedure: Thyroid ultrasonography
Ultrasound-guided thyroid fine-needle aspiration biopsy

  Eligibility

Ages Eligible for Study:   15 Years to 89 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Endocrinology Clinic

Criteria

Inclusion Criteria:

  • Subjects with thyroid nodules over 10 mm in the longest diameter
  • Euthyroid or hypothyroid subjects with a solitary thyroid nodule or multinodular goiter
  • Subjects with a hypoactive nodule in the thyroid scan and a low TSH

Exclusion Criteria:

  • Subjects with four or more thyroid nodules that are over 10 mm
  • Subjects with low TSH and hyperactive nodule on thyroid scan
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00571090

Locations
Turkey
Group Florence Nightingale
Istanbul, Turkey
Sponsors and Collaborators
Istanbul Science University
Group Florence Nightingale
Investigators
Principal Investigator: Ahmet Selcuk Can, MD Istanbul Science University and Group Florence Nightingale
  More Information

Additional Information:
Publications:
Responsible Party: Ahmet Selcuk Can, Associate Professor of Medicine, Istanbul Science University
ClinicalTrials.gov Identifier: NCT00571090     History of Changes
Other Study ID Numbers: B.30.2.IBU.0.01.00.00/511, 511
Study First Received: December 10, 2007
Last Updated: March 28, 2014
Health Authority: Turkey: Ministry of Health

Keywords provided by Istanbul Science University:
Thyroid nodule
Biopsy, Fine-Needle

Additional relevant MeSH terms:
Thyroid Neoplasms
Thyroid Diseases
Thyroid Nodule
Endocrine Gland Neoplasms
Neoplasms by Site
Neoplasms
Head and Neck Neoplasms
Endocrine System Diseases

ClinicalTrials.gov processed this record on April 17, 2014