The Specific Lung Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Supine and Prone Position

This study is currently recruiting participants. (see Contacts and Locations)
Verified May 2013 by Policlinico Hospital
Sponsor:
Information provided by (Responsible Party):
Davide Chiumello, Policlinico Hospital
ClinicalTrials.gov Identifier:
NCT00568659
First received: December 5, 2007
Last updated: May 15, 2013
Last verified: May 2013
  Purpose

The investigators aim is to study the specific lung elastance in ALI/ARDS patients during invasive mechanical ventilation, in supine and prone position.


Condition Intervention
Acute Lung Injury
Acute Respiratory Distress Syndrome
Procedure: specific elastance

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Safety Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: The Specific Lung Elastance in ALI/ARDS Patients in Supine and Prone Position

Resource links provided by NLM:


Further study details as provided by Policlinico Hospital:

Primary Outcome Measures:
  • Specific elastance [ Time Frame: 5 minutes ] [ Designated as safety issue: No ]

Estimated Enrollment: 15
Study Start Date: December 2007
Estimated Study Completion Date: January 2015
Primary Completion Date: November 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1 Procedure: specific elastance
The investigators study the specific lung elastance in ALI/ARDS patients in supine and prone position.

Detailed Description:

In sedated and paralyzed ALI/ARDS patients, we study and compare the specific lung elastance in supine and prone position during invasive mechanical ventilation.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • ALI/ARDS patients during invasive mechanical ventilation

Exclusion Criteria:

  • Haemodynamic failure, pneumothorax
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00568659

Contacts
Contact: Davide Chiumello, MD +39-0255033237 chiumello@libero.it

Locations
Italy
Policlinico Hospital Recruiting
Milano, Italy, 20122
Contact: Davide Chiumello, MD    +39-0255033237    chiumello@libero.it   
Sponsors and Collaborators
Policlinico Hospital
Investigators
Principal Investigator: Davide Chiumello, MD Policlinico Hospital
  More Information

No publications provided

Responsible Party: Davide Chiumello, MD, Policlinico Hospital
ClinicalTrials.gov Identifier: NCT00568659     History of Changes
Other Study ID Numbers: 1111
Study First Received: December 5, 2007
Last Updated: May 15, 2013
Health Authority: Italy: National Monitoring Centre for Clinical Trials - Ministry of Health

Keywords provided by Policlinico Hospital:
Gas exchange
Respiratory mechanics
Ventilator Induced Lung Injury

Additional relevant MeSH terms:
Syndrome
Respiratory Distress Syndrome, Newborn
Lung Injury
Respiratory Distress Syndrome, Adult
Acute Lung Injury
Disease
Pathologic Processes
Lung Diseases
Respiratory Tract Diseases
Respiration Disorders
Infant, Premature, Diseases
Infant, Newborn, Diseases
Thoracic Injuries
Wounds and Injuries

ClinicalTrials.gov processed this record on October 01, 2014