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Pain Processing in Anxiety and Depression

This study has been completed.
Sponsor:
Information provided by:
Danish Pain Research Center
ClinicalTrials.gov Identifier:
NCT00560196
First received: November 16, 2007
Last updated: October 7, 2009
Last verified: August 2009
History of Changes
  Purpose

The purpose of the study is to investigate pain, anxiety and depression in patients with panic anxiety disorders without pain or depression without pain compared with healthy volunteers


Condition Intervention
Pain
Anxiety
Depression
 Other: Observation

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Pain, Anxiety and Depression in Patients With Panic Anxiety Disorders Without Pain or Depression Without Pain Compared With Healthy Volunteers

Resource links provided by NLM:

MedlinePlus related topics: Anxiety Depression
U.S. FDA Resources

Further study details as provided by Danish Pain Research Center:

Primary Outcome Measures:
  • Quantitative sensory testing [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Symptom checklist 92 [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Hamilton Depression and Anxiety Rating Scale [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Major Depression Inventory [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • GAD-10 Anxiety Scale [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Health Survey SF-36 [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • McGill Pain Questionnaire [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Sweat test [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Heart rate variability testing [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Coping Strategy Questionnaire [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Pain Catastrophizing Scale [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Pain rating (VAS) [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]
  • Interview [ Time Frame: 3-4 hours ] [ Designated as safety issue: No ]

Enrollment: 71
Study Start Date: November 2007
Study Completion Date: February 2009
Groups/Cohorts Assigned Interventions
1
Patients with panic anxiety disorder without pain
 Other: Observation
N.A.
2
Patients with depression without pain
 Other: Observation
N.A.
3
Healthy controls
 Other: Observation
N.A.

  Eligibility

Ages Eligible for Study:   18 Years to 75 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Outpatient clinic Primary care clinic Community sample

Criteria

Inclusion Criteria:

  • Patients with panic disorder or depression

Exclusion Criteria:

  • Treatment with antidepressants, anticonvulsants or any other pain medication except paracetamol, SSRI and benzodiazepines
  • Serious or unstable medical disease
  • Prior or present diagnosis of mania, bipolar or psychotic disorder, delirium, suicidal, drug and alcohol dependence, severe agitation
  • Patients who cannot cooperate and do not understand Danish
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00560196

Locations
Denmark
Danish Pain Research Center, Aarhus University Hospital
Aarhus, Denmark, 8000
Sponsors and Collaborators
Danish Pain Research Center
Investigators
Principal Investigator: Lise Gormsen, MD Danish Pain Research Center, Aarhus University Hospital
  More Information

No publications provided

Responsible Party: Dr. Lise Gormsen, Danish Pain Research Center
ClinicalTrials.gov Identifier: NCT00560196     History of Changes
Other Study ID Numbers: PAD2007LG, N.A.
Study First Received: November 16, 2007
Last Updated: October 7, 2009
Health Authority: Denmark: Danish Dataprotection Agency

Keywords provided by Danish Pain Research Center:
Neuropathic pain
Chronic pain
Depression
Anxiety

Additional relevant MeSH terms:
Anxiety Disorders
Depression
Depressive Disorder
 Mental Disorders
Behavioral Symptoms
Mood Disorders

ClinicalTrials.gov processed this record on May 21, 2013