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Myocardial Injury is Not Related to Training Levels Among Recreational Participants in the Silicon Valley Marathon

This study has been completed.
Abbott Point-of-Care
Information provided by:
Stanford University Identifier:
First received: November 15, 2007
Last updated: November 16, 2007
Last verified: May 2007

To determine if pre-race training effects heart damage induced by marathon running.

Natriuretic Peptide, Brain

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Myocardial Injury is Not Related to Training Levels Among Recreational Participants in the Silicon Valley Marathon

Resource links provided by NLM:

Further study details as provided by Stanford University:

Enrollment: 53
Study Start Date: January 2006
Study Completion Date: October 2006
Detailed Description:

Investigations have shown increases in cardiac markers consistent with myocardial injury and left ventricular dysfunction in both recreational and elite athletes after endurance exercise. Pre-race training is an important component of endurance events, yet its effect on cardiovascular injury is unclear. The present study aimed to evaluate the correlation between myocardial injury and training level in recreational marathon runners utilizing both objective and subjective measures.


Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Any healthy male or female aged 18-65 planning to run the 2006 Silicon Valley Marathon.

Exclusion Criteria:

  • Hypertension
  • Hyperlipidemia
  • Diabetes
  • History of myocardial infarction or acute coronary syndrome
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00560040

Sponsors and Collaborators
Stanford University
Abbott Point-of-Care
Principal Investigator: Suzanne M Miller, MD Stanford Hospital and Clinics
  More Information

No publications provided Identifier: NCT00560040     History of Changes
Other Study ID Numbers: Miller 01
Study First Received: November 15, 2007
Last Updated: November 16, 2007
Health Authority: United States: Institutional Review Board

Keywords provided by Stanford University:
Natriuretic Peptide, Brain
Echocardiography processed this record on November 25, 2014