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Study of Inhaled Glucocorticosteroid Administration in Asthma Patients

This study has been completed.
Information provided by:
Hamamatsu University Identifier:
First received: November 15, 2007
Last updated: March 13, 2009
Last verified: March 2009

Once-daily inhaled glucocorticosteroids treatment can sufficiently control airway inflammation in asthma patients.

Condition Intervention Phase
Drug: Budesonide,hydrofluoroalkane-beclomethasone dipropionate
Drug: Budesonide,hydrofluoroalkane-beclomethasone
Phase 4

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Cross-Sectional
Official Title: Phase 4 Study of Once-Daily Inhaled Glucocorticosteroid Administration in Asthma Patients

Resource links provided by NLM:

Further study details as provided by Hamamatsu University:

Primary Outcome Measures:
  • once-daily administration of inhaled glucocorticosteroids can control airway inflammation [ Time Frame: two-year ]

Enrollment: 24
Study Start Date: November 2005
Study Completion Date: March 2007
Groups/Cohorts Assigned Interventions
receive once-daily administration of inhaled glucocorticosteroids at bedtime
Drug: Budesonide,hydrofluoroalkane-beclomethasone
once-daily administration at bedtime
receive twice-daily administration of inhaled glucocorticosteroids
Drug: Budesonide,hydrofluoroalkane-beclomethasone dipropionate
receive twice-daily administration


Ages Eligible for Study:   20 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

University Hospital


Inclusion Criteria:

  • Receive ICS for one year or more, with no change in dose within the previous 8 weeks

Exclusion Criteria:

  • Two or more courses of oral corticosteroid in the previous 12 months
  • Admission to hospital due to asthma in the previous 6 months
  • Admission to the intensive care unit due to asthma at any time in the past
  • Current cigarette smoker.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00559689

Hamamatsu University School of Medicine
Hamamatsu, Japan, 431-3192
Sponsors and Collaborators
Hamamatsu University
Study Chair: Kingo Chida, MD,PhD
  More Information

No publications provided Identifier: NCT00559689     History of Changes
Other Study ID Numbers: Hamamatsu-17-43, H-17-43
Study First Received: November 15, 2007
Last Updated: March 13, 2009
Health Authority: Japan: Institutional Review Board

Keywords provided by Hamamatsu University:
asthma patients

Additional relevant MeSH terms:
Bronchial Diseases
Hypersensitivity, Immediate
Immune System Diseases
Lung Diseases
Lung Diseases, Obstructive
Respiratory Hypersensitivity
Respiratory Tract Diseases
Anti-Asthmatic Agents
Anti-Inflammatory Agents
Autonomic Agents
Bronchodilator Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Peripheral Nervous System Agents
Pharmacologic Actions
Physiological Effects of Drugs
Respiratory System Agents
Therapeutic Uses processed this record on November 20, 2014