Tracheobronchomalacia: Treatment Outcomes
The purpose of this study is to evaluate respiratory symptoms and their impact in the quality of life and after treatment of the respiratory condition (tracheobronchomalacia - TBM).
|Study Design:||Time Perspective: Prospective|
|Official Title:||Tracheobronchomalacia: Treatment Outcomes|
- To evaluate the effect of central airway stabilization on symptoms and quality of life in patients with symptomatic and severe tracheobronchomalacia. [ Time Frame: At 10-14 days post-stent ; at 3 months and yearly post-tracheobronchoplasty ] [ Designated as safety issue: No ]
- To evaluate the effect of central airway stabilization on lung function, exercise capacity and functional status. [ Time Frame: At 10-14 days post-stent ; at 3 months and yearly post-tracheobronchoplasty ] [ Designated as safety issue: No ]
|Study Start Date:||January 2002|
|Study Completion Date:||March 2010|
|Primary Completion Date:||March 2010 (Final data collection date for primary outcome measure)|
TBM is an abnormal collapse of the tracheal and bronchial walls. It is characterized by flaccidity of the supporting tracheal and bronchial structures and a significant reduction of airway diameter on expiration seen in the trachea and/or in the mainstem bronchi. Currently there is no available data on the efficacy of central airway stabilization for treating TBM.
Our study would provide this important information and would establish the effect of central airway stabilization on symptoms, functional status, quality of life, lung function and exercise capacity in patients with symptomatic and severe TBM.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00550602
|United States, Massachusetts|
|Beth Israel Deaconess Medical Center- Division of Interventional Pulmonology|
|Boston, Massachusetts, United States, 02215|
|Principal Investigator:||Armin Ernst, M.D. FCCP||Beth Israel Deaconess Medical Center|