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Arterial Stiffness and Calcifications in Incident Renal Transplant Recipients (ASCIT)

This study is currently recruiting participants.
Verified October 2011 by Universitaire Ziekenhuizen Leuven
Sponsor:
Information provided by (Responsible Party):
Kathleen Claes, Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier:
NCT00547040
First received: October 18, 2007
Last updated: October 5, 2011
Last verified: October 2011
History of Changes
  Purpose

The purpose of this study is to determine the:

  • Natural history of calcification posttransplantation
  • Natural history of BMC following renal transplantation
  • Reverse correlation between calcification score and aortic calcifications following renal transplantation
  • Correlation of IMT, BMC, PWV and biochemical variables
  • Correlation of IMT, BMC, PWV, biochemical variables and outcome
  • Predictors of CV disease after transplantation
  • Predictors of IMT progression, BMC loss and PWV progression after renal transplantation

Condition Intervention
Renal Transplant
Atherosclerosis
Arterial Stiffness
 Other: no intervention

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Arterial Stiffness and Calcifications in Incident Renal Transplant Recipients

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Universitaire Ziekenhuizen Leuven:

Primary Outcome Measures:
  • cardiovascular outcome [ Time Frame: 5 years ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples Without DNA

serum, plasma, urine


Estimated Enrollment: 100
Study Start Date: October 2006
Estimated Study Completion Date: October 2013
Groups/Cohorts Assigned Interventions
A
incident renal transplant patients
 Other: no intervention
no intervention

  Eligibility

Ages Eligible for Study:   18 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

incident renal transplant recipients

Criteria

Inclusion Criteria:

  • Incident renal transplant patients or combined renal/pancreas transplant patients
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00547040

Contacts
Contact: kathleen Claes, MD 0032/16344580 kathleen.claes@uz.kuleuven.ac.be

Locations
Belgium
UZ Gasthuisberg Recruiting
Leuven, Belgium, 3000
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven
Investigators
Principal Investigator: kathleen Claes, MD UZ Leuven
Principal Investigator: kathleen claes, md UZ Leuven
  More Information

No publications provided

Responsible Party: Kathleen Claes, md, Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier: NCT00547040     History of Changes
Other Study ID Numbers: ML3775
Study First Received: October 18, 2007
Last Updated: October 5, 2011
Health Authority: Belgium: Institutional Review Board

Keywords provided by Universitaire Ziekenhuizen Leuven:
calcification
bone lesions

Additional relevant MeSH terms:
Atherosclerosis
Calcinosis
Arteriosclerosis
Arterial Occlusive Diseases
 Vascular Diseases
Cardiovascular Diseases
Calcium Metabolism Disorders
Metabolic Diseases

ClinicalTrials.gov processed this record on May 23, 2013