Text Size

The Effect of Fruit and Fruit Juice on Plasma Total Antioxidant Capacity

This study has been completed.
Sponsor:
Information provided by:
Maastricht University Medical Center
ClinicalTrials.gov Identifier:
NCT00545415
First received: October 11, 2007
Last updated: July 15, 2009
Last verified: July 2009
History of Changes
  Purpose

The aim of the study is to compare the effect of consumption of a fruit beverage on plasma antioxidant capacity with that of the consumption of fruit.


Condition Intervention
Healthy
 Dietary Supplement: Order 1
Dietary Supplement: Order 2
Dietary Supplement: Order 3
Dietary Supplement: Order 4
Dietary Supplement: Order 5
Dietary Supplement: Order 6

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Bio-equivalence Study
Intervention Model: Crossover Assignment
Masking: Open Label
Official Title: The Effect of Fruit and Fruit Juice on Plasma Total Antioxidant Capacity

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Maastricht University Medical Center:

Primary Outcome Measures:
  • The total plasma antioxidant capacity after intake of three different kinds of fruit(beverage) [ Time Frame: 3 weeks ] [ Designated as safety issue: No ]

Enrollment: 24
Study Start Date: January 2008
Study Completion Date: November 2008
Primary Completion Date: August 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1 Dietary Supplement: Order 1

Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands.

Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 2 Dietary Supplement: Order 2

Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands.

Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 3 Dietary Supplement: Order 3

Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands.

Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 4 Dietary Supplement: Order 4

Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands.

Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 5 Dietary Supplement: Order 5

Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands.

Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 6 Dietary Supplement: Order 6

Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands.

Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy males
  • body mass index between 20-25

Exclusion Criteria:

  • use of any medication
  • smoking
  • consumption of 3 or more glasses of alcohol per day
  • involved in top sport
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00545415

Locations
Netherlands
University of Maastricht
Maastricht, Netherlands, 6229 ER
Sponsors and Collaborators
Maastricht University Medical Center
Investigators
Principal Investigator: Aalt Bast, Prof. Dr. Maastricht University
  More Information

No publications provided

Responsible Party: Aalt Bast, Prof. Dr., Maastricht University
ClinicalTrials.gov Identifier: NCT00545415     History of Changes
Other Study ID Numbers: MEC-07-3-043
Study First Received: October 11, 2007
Last Updated: July 15, 2009
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Keywords provided by Maastricht University Medical Center:
fruit
antioxidant
Healthy subjects

Additional relevant MeSH terms:
Antioxidants
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Protective Agents
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on May 21, 2013