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Structured Stroke Management Improves Outcome at 6 Months

This study has been completed.
Sponsor:
Collaborator:
407 Doctors
Information provided by:
Kantonsspital Baden
ClinicalTrials.gov Identifier:
NCT00544622
First received: October 12, 2007
Last updated: October 16, 2008
Last verified: October 2008
History of Changes
  Purpose

Background/Aim of the study: To further reduce the 6 months stroke morbidity and mortality in a high volume stroke hospital and to compare the results with national and international data.

Methods: 204 consecutive stroke patients are analyzed in a prospective study in a single center teaching institution. The intervention consists of a structured therapeutic chain of 290 collaborating GPs, a standardised acute hospital proceeding overlapping with an early integrated neurovascular rehabilitation within the same institution. Primary endpoints include death and dependence at 6 months, secondary endpoints are the length of hospital stay (LOS) and the quantitative analysis of physical and psychosocial impairments. The data are directly compared with the same endpoints of the Swiss subgroup of the international stroke trial (IST).


Condition Intervention
Stroke
 Procedure: structured therapeutic chain of stroke treatment

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Official Title: Structured Stroke Management Improves Outcome at 6 Months

Resource links provided by NLM:

MedlinePlus related topics: Rehabilitation
U.S. FDA Resources

Further study details as provided by Kantonsspital Baden:

Primary Outcome Measures:
  • Mortality, dependence, psychoscial outcome
  • Mortality, dependence and psychosocial outcome [ Time Frame: 6 months endpoint ]

Study Start Date: January 2002
Estimated Study Completion Date: March 2003
  Eligibility

Ages Eligible for Study:   20 Years and older
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • An acute cerebrovascular event (ischemic stroke or intra-cerebral bleeding (ICB)) with the signs and symptoms of an acute stroke according to the World Health Organisation definition of acute stroke14 within the last 12 hours without the need or possibility of a neurosurgical intervention
  • No thrombolytic therapy within the first 3 hours (in order to allow the correct comparison with the Swiss cohort of the IST trial
  • The informed consent of the patient or, if not possible, of the relatives
  • Living at home before the event
  • Lack of participation in another trial.

Exclusion Criteria:

  • Thrombolytic therapy within the first 3 hours (in order to allow the correct comparison with the Swiss cohort of the IST trial
  • No informed consent of the patient or, if not possible, of the relatives
  • Not living at home before the event
  • Participation in another trial (26 patients were excluded because of TIA with full recovery within 24 hours after the event)
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00544622

Sponsors and Collaborators
Kantonsspital Baden
407 Doctors
Investigators
Study Chair: Juerg H. Beer, MD Department of Medicine
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00544622     History of Changes
Other Study ID Numbers: INR50
Study First Received: October 12, 2007
Last Updated: October 16, 2008
Health Authority: Switzerland: Federal Office of Public Health

Keywords provided by Kantonsspital Baden:
Stroke treatment
Rehabilitation
Stroke chain
Stroke unit

Additional relevant MeSH terms:
Stroke
Cerebral Infarction
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
 Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Brain Infarction
Brain Ischemia

ClinicalTrials.gov processed this record on May 23, 2013