Functional Organization of Somatosensory Responses in the Secondary Somatosensitive Area and Insula
The implication of the second somatosensory area (SII) and the insular cortex in the processing of somatosensory inputs is now well established. However the functional anatomy of these areas hidden in the depth of the sylvian scissure remain mostly unknown.
The aim of this fMRI study is to determine the functional cartography of SII and insula. The localization of responses to different somatosensory stimuli (slight touch, warm, cold, heat pain and arthrokinesia) applied on the left hand of 25 healthy volunteers, will be compared.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Functional Organization of Somatosensory Responses in the Secondary Somatosensitive Area (SII) and Insula : an fMRI Study|
- Comparison of euclidian distances between the centroids of clusters activations for the different types of stimulations into SII and insula. [ Time Frame: one day ] [ Designated as safety issue: No ]
- Determine the Talairach coordinates of the centroids of clusters of activations for the different types of somatosensory stimuli into SII and insula [ Time Frame: one day ] [ Designated as safety issue: No ]
|Study Start Date:||October 2007|
|Study Completion Date:||April 2008|
|Primary Completion Date:||April 2008 (Final data collection date for primary outcome measure)|
localization of the several types of somatosensory stimuli
Aims : Demonstrate that localization of the several types of somatosensory stimuli is different into SII and into insula. If possible, we'll determine a functional cartography of these areas.
|Service de Neurologie - CHU de Saint-Etienne|
|Saint-Etienne, France, 42055|
|Principal Investigator:||Laure Mazzola, MD||CHU de Saint-Etienne|