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Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women

This study has been completed.
Sponsor:
Collaborator:
Nu Skin Enterprises
Information provided by (Responsible Party):
Alfred Lane, Stanford University
ClinicalTrials.gov Identifier:
NCT00541931
First received: October 5, 2007
Last updated: December 12, 2012
Last verified: December 2012
History of Changes
  Purpose

We are seeking healthy female volunteers to determine if multinutrient supplementation affects visible signs of skin aging as well as blood measurements of aging. We are seeking smokers and non-smokers.


Condition Intervention
Skin Diseases
 Drug: Dietary Supplement: LifePak Nano

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Stanford University:

Primary Outcome Measures:
  • Determine whether supplementation affects skin aging [ Time Frame: Three months ] [ Designated as safety issue: No ]
    Assessment of metabolome and facial photographs


Secondary Outcome Measures:
  • Determine if supplementation affects blood markers of aging [ Time Frame: Three months ] [ Designated as safety issue: No ]
    Metabolomic analysis, arNOX analysis


Enrollment: 71
Study Start Date: October 2007
Study Completion Date: January 2012
Primary Completion Date: March 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Nonsmoker
Nonsmokers
 Drug: Dietary Supplement: LifePak Nano
Daily use
Other Name: Life Pak Nano
Smoker
Smoker arm
 Drug: Dietary Supplement: LifePak Nano
Daily use
Other Name: Life Pak Nano

  Eligibility

Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:- Fitzpatrick Skin type I or II

  • Nonpregnant Females, age 18-30 or 50-70
  • Body Mass Index Normal or Overweight
  • If age 18-30, must be non-smoker
  • Willing to fast for 8 hours prior to a blood draw
 Exclusion Criteria:- History of cosmetic surgery
  • Use of anti-aging medications within 3 months of enrollment
  • Use of over-the-counter anti-aging creams (not sunscreens) more than once per week within one month of enrollment
  • Use of dietary supplements including vitamins within one month of enrollment
  • Use of tanning beds or excessive UV exposure (greater than 2 hours per day) within one month of enrollment
  • Use of sunless tanners within one month of enrollment
  • Uncontrolled or ongoing serious medical condition
  • Participation in another clinical study involving use of an investigational drug or product
  • Medical condition which, at the discretion of the investigator, will have a significant impact on ability to judge participant's skin characteristics, including age.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00541931

Locations
United States, California
Stanford University School of Medicine
Stanford, California, United States, 94305
Sponsors and Collaborators
Stanford University
Nu Skin Enterprises
Investigators
Principal Investigator: Dr. Anne Lynn S. Chang Stanford University
  More Information

No publications provided

Responsible Party: Alfred Lane, Professor, Stanford University
ClinicalTrials.gov Identifier: NCT00541931     History of Changes
Other Study ID Numbers: 10622
Study First Received: October 5, 2007
Last Updated: December 12, 2012
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Skin Diseases

ClinicalTrials.gov processed this record on May 21, 2013