Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
AstraZeneca
ClinicalTrials.gov Identifier:
NCT00536796
First received: September 27, 2007
Last updated: October 29, 2014
Last verified: October 2014
  Purpose

A cholesterol/lipid profile screening project of high risk patients with hyperlipidaemia (secondary prevention) who already receive cholesterol-lowering therapy. Lipid profile and rate of patients who are treated to target (which is <100mg/dl for patients with high risk and <70mg/dl for patients at very high risk) are screened (hospital-based specialists). The doctors therapy decisions after the screening and possible reasons for these decisions will be documented. Our aim is to evaluate dosing habits, to evaluate how many patients are treated to their LDL-C target and to underline the importance of treating patients to their cholesterol targets.


Condition
Hyperlipidemias
Atherosclerosis
Coronary Heart Disease
Carotid Stenosis
Peripheral Vascular Diseases
Diabetes Mellitus

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Non-interventional Study Investigating How Effective Secondary Prevention Patients Are Treated to Their LDL-C Targets

Resource links provided by NLM:


Further study details as provided by AstraZeneca:

Primary Outcome Measures:
  • Cholesterol levels [ Time Frame: After 4 weeks ] [ Designated as safety issue: No ]
    Cholesterol levels from high risk patients after 4 weeks of cholesterol-lowering drug therapy under target values


Enrollment: 1096
Study Start Date: September 2007
Study Completion Date: December 2007
Primary Completion Date: December 2007 (Final data collection date for primary outcome measure)
Groups/Cohorts
Patients at very high risk
Patients at high risk
Patients at medium risk
Patients at low risk

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Male and female secondary prevention patients with: coronary disease with event: acute coronary syndrome, status post MI, PTCA, CABG, angiographically verified), PAVK (min. IIb or S.p. revascularization), stroke/TIA, carotis-plaque (asymptomatic min. 70% or S.p. revascularization), Diabetes Mellitus (type I, II)

Criteria

Inclusion Criteria:

  • Secondary prevention patients with hyperlipidemia and atherosclerosis (coronary heart disease, carotid stenosis, PVD, etc.) and/or diabetes who already receive cholesterol-lowering therapy

Exclusion Criteria:

  • Patients who do not receive cholesterol-lowering therapy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00536796

Locations
Austria
Research Site
Rohrbach, Upper Austria, Austria
Sponsors and Collaborators
AstraZeneca
Investigators
Study Chair: Josef Patsch, MD Chair of the Austrian Atheroslerosis Society
Study Chair: Bernhard Foger, MD Co-Chair of the Austrian Atheroslerosis Society
  More Information

No publications provided

Responsible Party: AstraZeneca
ClinicalTrials.gov Identifier: NCT00536796     History of Changes
Other Study ID Numbers: NIS-CAT-CRE-2007/2
Study First Received: September 27, 2007
Last Updated: October 29, 2014
Health Authority: Not required for this study:

Keywords provided by AstraZeneca:
Hyperlipidemia
Need-to-treat
NIS
Secondary prevention patients with hyperlipidemia and atherosclerosis (coronary heart disease, carotid stenosis, PVD, etc.) and/or diabetes

Additional relevant MeSH terms:
Arteriosclerosis
Atherosclerosis
Carotid Stenosis
Coronary Artery Disease
Coronary Disease
Diabetes Mellitus
Heart Diseases
Hyperlipidemias
Myocardial Ischemia
Peripheral Arterial Disease
Peripheral Vascular Diseases
Vascular Diseases
Arterial Occlusive Diseases
Brain Diseases
Cardiovascular Diseases
Carotid Artery Diseases
Central Nervous System Diseases
Cerebrovascular Disorders
Dyslipidemias
Endocrine System Diseases
Glucose Metabolism Disorders
Lipid Metabolism Disorders
Metabolic Diseases
Nervous System Diseases

ClinicalTrials.gov processed this record on October 29, 2014