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| Sponsored by: |
Kaunas University of Medicine |
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| Information provided by: | Kaunas University of Medicine |
| ClinicalTrials.gov Identifier: | NCT00528476 |
Purpose
The purpose of this study is to determine clinical and urodynamic risk factors for recurrent urinary tract infection in 5-18 years old children.
| Condition |
|---|
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Urinary Tract Infection Pyelonephritis Cystitis |
| Study Type: | Observational |
| Study Design: | Natural History, Longitudinal, Case Control, Prospective Study |
| Official Title: | Role of Clinical and Urodynamic Risk Factors for Recurrent Urinary Tract Infection in 5-18 Years Old Children |
| Enrollment: | 161 |
| Study Start Date: | November 2004 |
| Study Completion Date: | January 2007 |
| Groups/Cohorts |
|---|
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1: Case
Patients, who were treated because of recurrent (2 or more urinary tract infections per year) pyelonephritis or cystitis.
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2: Control
Patients with nonrecurrent urinary tract infections (patients who had no history of more than one urinary tract infections in last year).
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It is known, that in the group of young children the most common reason of recurrent UTI is anatomic abnormalities, such as vesicoureteral reflux, hydronephrosis. However, not all recurrent UTI can be explained by anatomic abnormalities. The vast majority of school age children with recurrent UTI have anatomically normal urinary tract. Recent studies discuss about the role of behavioral and functional abnormalities (inadequate fluid intake, stool retention, infrequent voiding, etc.) that can predispose recurrent urinary tract infections. Influence of some these abnormalities for recurrent UTI is controversial. Family history, behavioral and functional abnormalities which predispose to urinary tract infections in children with normal urinary tract are neglected in most protocols of urinary tract infection.
Children in this study receive a careful evaluation including complete history, voiding-drinking diary, bowel questionnaire, physical investigation, sonography, voiding cystourethrogram.
Follow up time - 1 year. Urinalysis once a month and during each episode of fever.
Eligibility| Ages Eligible for Study: | 5 Years to 18 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Lithuania | |
| Kaunas University of Medicine | |
| Kaunas, Lithuania, 44307 | |
| Principal Investigator: | Sarunas Rudaitis, MD | Clinic of Children's Diseases, Kaunas University of Medicine |
| Study Chair: | Birute Pundziene, MD, PhD | Clinic of Children's Diseases, Kaunas University of Medicine |
More Information
| Study ID Numbers: | BE-2-68 |
| Study First Received: | September 10, 2007 |
| Last Updated: | September 11, 2007 |
| ClinicalTrials.gov Identifier: | NCT00528476 History of Changes |
| Health Authority: | Lithuania: State Medicine Control Agency - Ministry of Health |
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pyelonephritis cystitis risk factor children urodynamics |
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Cystocele Urologic Diseases Nephritis Pyelonephritis Urinary Bladder Diseases |
Urinary Tract Infections Cystitis Kidney Diseases Recurrence |
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Communicable Diseases Urologic Diseases Nephritis, Interstitial Nephritis Pyelonephritis Urinary Bladder Diseases |
Urinary Tract Infections Cystitis Kidney Diseases Infection Pyelitis |
