Retrospective Analysis of Clinical Features in Ventriculoperitoneal Shunt Infectionsin Adults

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Pittsburgh
ClinicalTrials.gov Identifier:
NCT00524108
First received: August 31, 2007
Last updated: August 14, 2012
Last verified: August 2012
  Purpose

The objectives of this study are:

  • To describe the incidence of clinical features in adults with internal ventriculoperitoneal (VP) shunt infections,
  • To determine the validity of laboratory parameters in adults with internal ventriculoperitoneal shunt infections and
  • To evaluate the relationship between the timing of shunt re-implantation with the rates of relapse and secondary infection.

Condition
Ventriculoperitoneal Shunt
Infection

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Retrospective Analysis of Clinical Features in Ventriculoperitoneal Shunt Infections and Time to Re-Implantation in Adults

Further study details as provided by University of Pittsburgh:

Enrollment: 350
Study Start Date: August 2007
Study Completion Date: December 2010
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Detailed Description:

Information from medical records of patients seen by the PI will be collected and analyzed to describe the incidence of clinical features in adults with internal ventriculoperitoneal shunt infections, to determine the validity of laboratory parameters in adults with internal ventriculoperitoneal shunt infections and to evaluate the relationship between the timing of shunt re-implantation with the rates of relapse and secondary infection.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

VP shunt infection

Criteria

Inclusion Criteria:

  • Adults (age >= 18 yrs) with VP shunts (ventriculoatrial [VA], and other cerebrospinal fluid [CSF] catheters will not be included).
  • Cases will include patients with a diagnosis of VP shunt infection.
  • Controls will be patients with a clinical suspicion of shunt infections with negative CSF cultures.

Exclusion Criteria:

  • Patients with meningitis from community acquired organisms (e.g. Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes and Haemophilus Influenzae).
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00524108

Locations
United States, Pennsylvania
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15213
Sponsors and Collaborators
University of Pittsburgh
Investigators
Principal Investigator: Adarsh Bhimraj, MD University of Pittsburgh
  More Information

No publications provided

Responsible Party: University of Pittsburgh
ClinicalTrials.gov Identifier: NCT00524108     History of Changes
Other Study ID Numbers: PRO07080212
Study First Received: August 31, 2007
Last Updated: August 14, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by University of Pittsburgh:
shunt
internal ventriculoperitoneal

Additional relevant MeSH terms:
Infection
Communicable Diseases

ClinicalTrials.gov processed this record on September 29, 2014