Detection and Treatment of Depression in Patients Admitted to the General Hospital
Recruitment status was Recruiting
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Purpose
Depression is a common disorder among patients with a somatic illness admitted to the general hospital. Patients with depression do worse in terms of their somatic symptoms or functioning that those without depression. They also stay in the hospital for longer.
That is the reason that we are interested to know whether patients with depression do better if their depression is recognised earlier and treated appropriately. We would like to find out which questionnaires are most suitable in clinical practice to help pick up patients with a depression. In addition, we would like to know whether a short-term psychological treatment of depression would be of any help. We hope to be able to show that this treatment would not only result in a reduction of depressive symptoms, but also in a better and quicker recovery of the somatic illness.
The treatment will consist of 6 to 9 weekly sessions of one hour, conducted by a cognitive behavioural assistant. Initially, the treatment will take place in the hospital. When patients are discharged, treatment sessions will continue at home. The treatment will focus on things like recognising and challenging unhelpful thoughts, planning of activities, and testing out of predictions by setting up behavioural experiments. Three monthly booster sessions will be offered to help patients to maintain their gains and prevent relapse. We will reassess the symptoms of the patients at three and six months after the end of treatment.
| Condition | Intervention | Phase |
|---|---|---|
|
Depressive Disorder Depression |
Behavioral: Cognitive Behavioural Therapy |
Phase 2 |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Investigator, Outcomes Assessor) Primary Purpose: Treatment |
- Depressive Disorder Physical symptoms [ Time Frame: 9 months ]
- - Functional impairment (RAND 36) - Cost-effectiveness (TiC-P) - Quality of Life (EQ5D) [ Time Frame: 9 months ]
| Estimated Enrollment: | 60 |
| Study Start Date: | August 2007 |
| Estimated Study Completion Date: | December 2008 |
| Estimated Primary Completion Date: | December 2008 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Active Comparator: 1
Cognitive Behavioural Therapy
|
Behavioral: Cognitive Behavioural Therapy |
|
No Intervention: 2
Treatment as Usual
|
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Depressive Disorder
Exclusion Criteria:
- Severe Physical Disfunction
- Severe Cognitive Disfunction
- Speech and/or Hearing Disorder
- Limited knowledge of the Dutch language
Contacts and Locations| Contact: Matthijs W. Beltman, MSc | +31 (0)24 3668008 | mw.beltman@psy.umcn.nl |
| Netherlands | |
| Radboud University Nijmegen Medical Centre | Recruiting |
| Nijmegen, Gelderland, Netherlands, 6500 HB | |
| Principal Investigator: | Anne EM Speckens, PhD, MD | Radboud University |
More Information
Additional Information:
No publications provided
| Responsible Party: | Anne EM Speckens, PhD, MD, Radboud University Medical Center |
| ClinicalTrials.gov Identifier: | NCT00521911 History of Changes |
| Other Study ID Numbers: | PROJECT9999 |
| Study First Received: | August 27, 2007 |
| Last Updated: | December 24, 2008 |
| Health Authority: | Netherlands: The Central Committee on Research Involving Human Subjects (CCMO) |
Keywords provided by Radboud University:
|
Intervention Studies Randomized Controlled Trials Cognitive Therapy Hospitals, General Prevalence |
Additional relevant MeSH terms:
|
Depression Depressive Disorder Behavioral Symptoms Mood Disorders Mental Disorders |
ClinicalTrials.gov processed this record on May 19, 2013