Does Sunbed Radiation With Mainly UVA Provoke Cutaneous Vitamin D Synthesis in Humans?

This study has been completed.
Hvidovre University Hospital
Information provided by:
Bispebjerg Hospital Identifier:
First received: August 14, 2007
Last updated: August 15, 2007
Last verified: August 2007

We would investigate in a controlled, randomized open study in the winter season: 1) If serum levels of vitamin D (25(OH)D) increase in subjects treated with sunbed with sunlamps emitting mainly UVA and only 0·5% or 1·4% UVB compared to non-sunbed treated controls 2) If yes, are the 25(OH)D serum levels then dependent on the UVB dose?

Condition Intervention
Radiation: UV radiation

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Pharmacokinetics Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: Sunbed Radiation Provoke Cutaneous Vitamin D Synthesis in Humans, a Randomized Controlled Trial

Resource links provided by NLM:

Further study details as provided by Bispebjerg Hospital:

Primary Outcome Measures:
  • Serum concentration of 25(OH)D [ Time Frame: 18 Days ]

Secondary Outcome Measures:
  • Serum concentration of PTH [ Time Frame: 18 Days ]

Enrollment: 41
Study Start Date: February 2006
Study Completion Date: April 2006
Arms Assigned Interventions
Active Comparator: UVB 0.5% Radiation: UV radiation
UV radiation with 99.5% UVA and 0.5%UVB
No Intervention: Controls
Active Comparator: UVB 1.4% Radiation: UV radiation
UVB 1.4 % and UVA 98.6


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Healthy
  • Females
  • Above 50 years
  • Younger with serum concentration of 25(OH)D below 50nmol/l

Exclusion Criteria:

  • No sunbed use last ½ year
  • No sun holiday last ½ year
  • No intake of vitamin D above 10 microgram/day
  Contacts and Locations
Please refer to this study by its identifier: NCT00516867

Bispebjerg Hospital
Copenhagen, Denmark, DK-2000 NV
Sponsors and Collaborators
Bispebjerg Hospital
Hvidovre University Hospital
Study Chair: Hans C Wulf, MD, DSc Bispebjerg Hospital
  More Information

No publications provided Identifier: NCT00516867     History of Changes
Other Study ID Numbers: KF 01 290815
Study First Received: August 14, 2007
Last Updated: August 15, 2007
Health Authority: Denmark: National Board of Health

Additional relevant MeSH terms:
Vitamin D
Bone Density Conservation Agents
Physiological Effects of Drugs
Pharmacologic Actions
Growth Substances processed this record on April 23, 2014