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Genetic Abnormalities and Biological Changes of Panic Disorder Patients After Pharmacotherapy

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2007 by Samsung Medical Center.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Samsung Medical Center
ClinicalTrials.gov Identifier:
NCT00515996
First received: August 13, 2007
Last updated: NA
Last verified: August 2007
History: No changes posted
  Purpose

We plan to examine genetic polymorphism of catechol-O-methyltransferase in panic disorder and neurobiological changes of panic disorder patients after 12 weeks of pharmacotherapy with paroxetine. We plan to include 40 panic disorder patients and 40 normal control subjects in this study for 3 years.


Condition
Panic Disorder

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Genetic Abnormalities and Changes of Autonomic Nervous System, Serotonin System, and Neuroendocrine System According to Pharmacotherapy in Panic Disorder

Resource links provided by NLM:

MedlinePlus related topics: Panic Disorder
Drug Information available for: Serotonin
U.S. FDA Resources

Further study details as provided by Samsung Medical Center:

Estimated Enrollment: 80
Study Start Date: January 2006
Estimated Study Completion Date: December 2008
Groups/Cohorts
Case: 2
paroxetine treatment group vs. normal control group

  Eligibility

Ages Eligible for Study:   20 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Panic disorder

Exclusion Criteria:

  • Other major medical or psychiatric illnesses
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00515996

Locations
Korea, Republic of
Samsung Medical Center Recruiting
Seoul, Korea, Republic of, 135-710
Contact: Tae Geun Kim, BA     82-2-3410-2975     tggo.kim@samsung.com    
Principal Investigator: Bum-Hee Yu, M.D. & Ph.D.            
Sponsors and Collaborators
Samsung Medical Center
Investigators
Principal Investigator: Bum-Hee Yu, M.D. & Ph.D. Samsung Medical Center, Sungkyunkwan University School of Medicine
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00515996     History of Changes
Other Study ID Numbers: C-A6-418-2
Study First Received: August 13, 2007
Last Updated: August 13, 2007
Health Authority: South Korea: Samsung Medical Center

Keywords provided by Samsung Medical Center:
panic disorder
paroxetine
genetic polymorphism
serotonin

Additional relevant MeSH terms:
Congenital Abnormalities
Panic Disorder
Anxiety Disorders
Mental Disorders

ClinicalTrials.gov processed this record on June 17, 2013