Influence of Paternal Age on Assisted Reproduction Outcome (MALE AGING)

This study has been completed.
Sponsor:
Information provided by:
Instituto Valenciano de Infertilidad, IVI VALENCIA
ClinicalTrials.gov Identifier:
NCT00510861
First received: August 1, 2007
Last updated: NA
Last verified: August 2007
History: No changes posted
  Purpose

In the recent years, there is an increasing tendency to the parenthood delay in developed countries, and there is not enough information available regarding the influence of the male's age on fertility. If any, the negative impact should be acting at advanced ages.

Our aim with this work was to determine the role of paternal age on IUI results embryo quality and IVF outcome. Evenmore, in order to standardize the female factor, good quality oocytes (from fertile oocyte donors) and only first IVF cycles in young women were considered.


Condition
We Will Retrospectively Assess Our Databases in Our Clinic:
Instituto Valenciano de Infertilidad in Valencia (Spain)
Searching for Assisted Reproduction Procedures
(IUI, Standard IVF/ICSI Cycles and Ovum Donation IVF/ICSI Cycles)
Who Were Referred to Our Unit to Cryopreserve Sperm During the Period
From January 2000 to December 2006.

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Cross-Sectional
Official Title: Influence of Paternal Age on Assisted Reproduction Outcome

Resource links provided by NLM:


Further study details as provided by Instituto Valenciano de Infertilidad, IVI VALENCIA:

Study Start Date: February 2007
Study Completion Date: May 2007
Detailed Description:

A retrospective study has been designed with a total number of 2204 IUI, 1286 IVF cycles and 1412 IVF cycles with donated oocytes from 2000 to 2006.

The inclusion criteria will be for IUI: women under 38 years old, tubal patency demonstrated by hysterosalpingography, normal uterine scan, normal basal hormonal levels, body mass index < 27 kg/m2, and absence of polycystic ovarian syndrome and endometriosis. For normal IVF cycles and oocyte donation cycles only first cycles will be analyzed. Cycles will be studied only in couples with absence of severe male factor.

  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • women under 38 years old, tubal patency demonstrated by hysterosalpingography, normal uterine scan, normal basal hormonal levels, body mass index < 27 kg/m2.

Exclusion Criteria:

  • absence of polycystic ovarian syndrome, hydrosalpinx or endometriosis.
  • Cycles were studied only in couples with absence of severe male factor.
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00510861

Locations
Spain
IVI
Valencia, Spain, 46015
Sponsors and Collaborators
Instituto Valenciano de Infertilidad, IVI VALENCIA
Investigators
Principal Investigator: Marcos Meseguer, PhD IVI Valencia
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00510861     History of Changes
Other Study ID Numbers: VLC-MM-0205-507-26
Study First Received: August 1, 2007
Last Updated: August 1, 2007
Health Authority: Spain: Ministry of Health

Keywords provided by Instituto Valenciano de Infertilidad, IVI VALENCIA:
male age, assisted reproduction, sperm, pregnancy outcome

ClinicalTrials.gov processed this record on October 29, 2014