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Tissue Engineering for Hair Follicle Regeneration

This study is currently recruiting participants.
Verified May 2006 by National Taiwan University Hospital
Sponsor:
Collaborators:
National Science Council, Taiwan
National Health Research Institutes, Taiwan
Information provided by:
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT00506636
First received: July 23, 2007
Last updated: NA
Last verified: May 2006
History: No changes posted
  Purpose

This study is to try to maintain cultured dermal papilla cells in spherical structure in vitro before transplanting into dermis in vivo. Also, this study is aimed in clarifying actual mechanism of inducing hair follicle by dermal papilla cells.


Condition Intervention
Tissue Engineering
Hair Follicle Regeneration
 Behavioral: Tissue engineering for hair follicle regeneration

Study Type: Observational
Study Design: Additional Descriptors: Convenience Sample
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: Study of Tissue Engineering for Hair Follicle Regeneration

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 400
Study Start Date: May 2006
Estimated Study Completion Date: December 2016
Detailed Description:

Hair transplantation is an well-documented way of treating hair loss. Hair transplantation is based on redistribution of hair follicles without any new follicle formation. It has been long that a lot of researchers have focused on developing skills in regenerating hair follicles. However, cultured dermal papilla cells lose the ability of inducing hair follicle formation after several generations in vitro culture. Our study is aiming in culturing dermal papilla cells in vitro and maintain their spherical structure before transplanting into dermis in vivo. Meantime, this study may help clarify the actual mechanism of inducing hair follicle by dermal papilla cells.

  Eligibility

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients receiving cosmetic surgeries such as removal of moles

Exclusion Criteria:

  • No special exclusion criteria
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00506636

Contacts
Contact: Sung-Jan Lin, MD PhD +886-2-23123456 ext 5323 jsjl2000tw@yahoo.com.tw

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: Sung-Jan Lin, MD PhD     +886-2-23123456 ext 5323     jsjl2000tw@yahoo.com.tw    
Sponsors and Collaborators
National Taiwan University Hospital
National Science Council, Taiwan
National Health Research Institutes, Taiwan
Investigators
Principal Investigator: Sung-Jan Lin, MD PhD National Taiwan University Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00506636     History of Changes
Other Study ID Numbers: 9561705025
Study First Received: July 23, 2007
Last Updated: July 23, 2007
Health Authority: Taiwan: Department of Health

ClinicalTrials.gov processed this record on May 21, 2013