B Cell Response to a Primary and a Booster Course of the Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Infants

Inclusion Criteria:

• healthy infants aged 2 months (56 - 83 days old, inclusive)
• mother available for blood draw at Visit 1

Exclusion Criteria:

• With known hypersensitivity to any vaccines contained within the routine immunization schedule.
• With unacceptable concurrent illnesses or conditions - e.g.: a severe acute or chronic illness; with any present or suspected serious disease such as metabolic, cardiac or autoimmune disease or insulin dependent diabetes or with any other serious disease (e.g., with signs of cardiac or renal failure or severe malnutrition), including progressive neurological disease; a genetic anomaly, e.g. Down's syndrome; any immunodeficiency, including use of systemic corticosteroids; born at less than 36 weeks gestation; weighing less than 2.5 kg at birth; previous clinical or bacteriological diagnosis of meningitis, or with a history of household contact or intimate exposure to an individual with culture proven Neisseria meningitidis disease; known bleeding diathesis, or any condition associated with a prolonged bleeding time;
• Who have received any prohibited prior or concomitant medications - e.g.: any immunizations within the 30 days prior to enrollment, with the exception of BVG or hepatitis B; immunoglobulin; any blood products