The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture

The recruitment status of this study is unknown because the information has not been verified recently.

Verified May 2007 by Hackensack University Medical Center. Recruitment status was Recruiting

First Received on May 30, 2007. No Changes Posted

Sponsor:	Hackensack University Medical Center
Information provided by:	Hackensack University Medical Center
ClinicalTrials.gov Identifier:	NCT00481585

Purpose

The objective of the present study is to determine whether or not primary human mammary epithelial cells are competent for use in molecular studies of transepithelial electrophysiology focusing on the function of the tight junction protein claudin 3.

Human breast Tissue will be removed from mastectomy specimens and used as a source to generate epithelial cells for study.

Condition
Breast Cancer

Study Type:	Observational
Study Design:	Observational Model: Defined Population Primary Purpose: Screening Time Perspective: Cross-Sectional Time Perspective: Prospective
Official Title:	The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture

Resource links provided by NLM:

Genetics Home Reference related topics: breast cancer

MedlinePlus related topics: Breast Cancer Cancer

U.S. FDA Resources

Further study details as provided by Hackensack University Medical Center:

Estimated Enrollment:	20
Study Start Date:	May 2007

Eligibility

Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Subjects of this pilot study are limited to those female patients who are undergoing therapeutic or prophylactic mastectomy procedures conducted by the department of Surgery at HUMC.

Exclusion Criteria:

From within this population, no exclusion criteria shall be applied based on age, race, ethnicity, gender, HIV status, or menopause.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00481585

Locations

United States, New Jersey
Hackensack Univeristy Medical Center	Recruiting
Hackensack, New Jersey, United States, 07601
Contact: William C. Black, M.D. 201-336-2794 wblack@humed.com
Principal Investigator: Erik F. Young, Ph.D.
Sub-Investigator: Richard J Davies, M.D.

Sponsors and Collaborators

Hackensack University Medical Center

Investigators

Principal Investigator:

Erik F Young, Ph.D.

Hackensack University Medical Center

More Information

No publications provided

ClinicalTrials.gov Identifier:	NCT00481585 History of Changes
Other Study ID Numbers:	07.01.041
Study First Received:	May 30, 2007
Last Updated:	May 30, 2007
Health Authority:	United States: Institutional Review Board

Keywords provided by Hackensack University Medical Center:

claudin
electrophysiology
breast
screening

Additional relevant MeSH terms:

Breast Neoplasms
Neoplasms by Site
Neoplasms
Breast Diseases
Skin Diseases

ClinicalTrials.gov processed this record on February 09, 2012