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Aerobic Capacity and Body Composition in Colon Cancer Patients
The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2008 by Alberta Health Services.   Recruitment status was  Active, not recruiting

First Received on May 7, 2007.   Last Updated on December 19, 2008   History of Changes
Sponsor: Alberta Health Services
Information provided by: Alberta Health Services
ClinicalTrials.gov Identifier: NCT00470782
  Purpose

Recent studies have shown that survival after a colorectal cancer diagnosis may be affected by a person's activity level and body size. This research says that for colorectal cancer patients, the less active and more obese they are, the more likely they are to have a cancer recurrence or die from their cancer. Chemotherapy has been shown to reduce activity levels, fitness, and body size in some cancer patients. However, it is not known how chemotherapy specific for colon cancer patients affects their activity levels, fitness, and body size. The main goal of our study will be to look at how chemotherapy treatments affect the fitness, activity levels, and body size in colon cancer patients. In order to do this, we will measure these variables before chemotherapy treatments, and at 1 and 6 months following the end of treatment. Our results will show how chemotherapy affects fitness, activity levels, and body size in colon cancer patients and provide data to help in designing an exercise intervention specifically for colon cancer survivors.


Condition
Colonic Neoplasms

Study Type: Observational
Official Title: Changes in Aerobic Capacity and Body Composition in Colon Cancer Patients Receiving Chemotherapy

Resource links provided by NLM:


Further study details as provided by Alberta Health Services:

Estimated Enrollment: 40
Study Start Date: October 2007
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • histologically confirmed colon cancer (Stage III and those Stage II patients deemed high-risk
  • approval of the treating oncologist
  • scheduled to received chemotherapy
  • able to understand and provide written informed consent in English
  • 18+ years of age
  • no uncontrolled co-morbidities (including hypertension, cardiac illness, psychiatric condition, etc.)
  • negative ECG as assessed during maximal graded exercise test

Exclusion Criteria:

  • metastatic or recurrent colon cancer patients
  • pregnancy
  • any uncontrolled medical condition that would be a contraindication to exercise (assessed by treating oncologist)
  • unwilling to attend, travel to or participate in the assessments at all 3 time points

In addition, 10 patients meeting all of the eligibility criteria who are not scheduled to receive chemotherapy will also be recruited to the study to serve as "surgery only" controls.

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00470782

Locations
Canada, Alberta
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2
Sponsors and Collaborators
Alberta Health Services
Investigators
Principal Investigator: Kerry Courneya, PhD University of Alberta
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00470782     History of Changes
Other Study ID Numbers: GI-5-0064
Study First Received: May 7, 2007
Last Updated: December 19, 2008
Health Authority: United States: Institutional Review Board

Keywords provided by Alberta Health Services:
colonic neoplasms
exercise
body composition
anthropometry

Additional relevant MeSH terms:
Neoplasms
Colonic Neoplasms
Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases

ClinicalTrials.gov processed this record on February 12, 2012