Evaluation of NT PRO BNP Guided Therapy on Hospitalization Rate and Mortality in Patients With Chronic HF NYHA II-IY
To use continuous measurement of NT Pro BNP level as guide in therapy patients with CHF.
Chronic Heart Failure
Procedure: Treatment according NT Pro BNP level
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Phase 1 Study of Using BNP as Guided Parameter in Treatment HF|
|Study Start Date:||June 2007|
|Study Completion Date:||March 2010|
|Primary Completion Date:||January 2010 (Final data collection date for primary outcome measure)|
Group of 100 patients with CHF, NYHA II-IY will be followed for 1 years in outpatient clinic of our hospital for hospitalization, death, 6 min walking protocol, number of decompensation as a primary end point. 50 patients will be treated according usual practice in outpatient clinics and in 50 patients will be additionally used level of NT Pro BNP as additional parameter.If level NT Pro BNP will be goes down will not be changes in treatment regiment. If level of NT Pro BNP will be increased treatment will be intensified.At the end of 1 year follow up we will compare the result of two strategies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00469001
|Hillel Yaffe Medical Center|
|Hadera, Israel, 38100|
|Principal Investigator:||Michael Shochat, MD, PhD||Hillel Yaffe Medical Center|