Diet and the Aging Brain

This study has been completed.
Sponsor:
Information provided by:
University Hospital Muenster
ClinicalTrials.gov Identifier:
NCT00463255
First received: April 18, 2007
Last updated: November 7, 2011
Last verified: November 2011
  Purpose

We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.


Condition Intervention Phase
Healthy
Behavioral: diet
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Phase IV Interventional Study: Effect of Diet on Brain Function in Elderly Healthy People

Further study details as provided by University Hospital Muenster:

Primary Outcome Measures:
  • implicit visual-motor learning of a finger sequence of the hand.

Secondary Outcome Measures:
  • implicit learning of an artificial language
  • several plasma levels related to cognitive functions

Estimated Enrollment: 120
Study Start Date: August 2006
Study Completion Date: October 2008
Detailed Description:

The age-related degradation of cognitive functions even to the point of neurodegenerative disorders such as alzheimer`s disease are a growing public-health concern with potentially devastating effects.

Refering to animal data and empirical studies, a healthy diet rich in unsaturated fatty acids and low in calories should improve cognitive functions such as learning and memory. To test this hypothesis, we study general brain functions in healthy elderly subjects (50-80 years old) during a short term diet.

  Eligibility

Ages Eligible for Study:   50 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy subjects
  • 50-80 years old
  • moderate to heavy weight
  • must be able to change diet at home

Exclusion Criteria:

  • diabetes
  • younger than 50 years
  • BMI < 23
  • already participating in other studys
  • MMSE > 26
  • eating disorders
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00463255

Locations
Germany
University Hospital Muenster, Department of Neurology
Muenster, NRW, Germany, 48149
Sponsors and Collaborators
University Hospital Muenster
Investigators
Study Chair: Stefan Knecht, MD, Prof. University Hospital Muenster
Study Chair: Bernd E Ringelstein, MD, Prof University Hopsital Muenster
Principal Investigator: Agnes Floeel, MD University Hospital Muenster
  More Information

Additional Information:
No publications provided

ClinicalTrials.gov Identifier: NCT00463255     History of Changes
Other Study ID Numbers: Ernaehrung-Neuromod 01
Study First Received: April 18, 2007
Last Updated: November 7, 2011
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by University Hospital Muenster:
Diet
elderly
age-related diseases
prevention
cognitive decline
Clinical study

ClinicalTrials.gov processed this record on July 29, 2014