Slowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis Pigmentosa

This study has been completed.
Sponsor:
Information provided by:
Azienda Policlinico Umberto I
ClinicalTrials.gov Identifier:
NCT00461435
First received: April 17, 2007
Last updated: NA
Last verified: April 2007
History: No changes posted
  Purpose

Our aim was to assess the role and usefulness of Hyperbaric oxygen therapy in a long lasting period, assessing its efficacy on rescuing retinal photoreceptors and preserving visual function in retinitis pigmentosa.


Condition Intervention
Retinitis Pigmentosa
Procedure: hyperbaric oxygen therapy

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind
Official Title: Slowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis Pigmentosa

Resource links provided by NLM:


Further study details as provided by Azienda Policlinico Umberto I:

  Eligibility

Ages Eligible for Study:   20 Years to 70 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Patients with clearly hereditary RP (we performed to all of them genetic analysis for rhodopsin, and peripherin genes, only 4 patient with ADRP showed point mutation 3 on codon 135 and 1 on codon 347); best corrected visual acuity (BCVA) ≥ 0.50 logMAR; visual field ≥ 3 degree diameter circle; recordable ERG.

Exclusion Criteria:

  • Exclusion criteria were: patients with sporadic RP; BCVA ≤ 0.50 logMAR; visual field ≤ 3 degree diameter circle; not recordable ERG.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00461435

Locations
Italy
Azienda Policlinico Umberto I
Rome, Italy, 00161
Sponsors and Collaborators
Azienda Policlinico Umberto I
Investigators
Principal Investigator: Enzo Maria Vingolo, PH.D. Policlinico Umberto I, Dipartimento di Oftalmologia
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00461435     History of Changes
Other Study ID Numbers: SS01
Study First Received: April 17, 2007
Last Updated: April 17, 2007
Health Authority: Italy:Italian National commitee for hyperbaric therapy

Additional relevant MeSH terms:
Retinitis
Retinitis Pigmentosa
Retinal Diseases
Eye Diseases
Eye Diseases, Hereditary
Retinal Dystrophies
Retinal Degeneration
Genetic Diseases, Inborn

ClinicalTrials.gov processed this record on April 14, 2014