Enhancing Utilization of Non-Invasive Positive Pressure Ventilation in Critical Care
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Purpose
Non-invasive positive pressure ventilation (NIV) refers to the provision of mechanical ventilation without an artificial airway (for example, an endotracheal tube). Over the past decade, evidence from randomized control trials has accumulated to demonstrate effectiveness of the technique in avoiding intubation, reducing complications associated with intubation, shortening ICU and hospital lengths of stay, and reducing mortality rates in selected patients with acute respiratory failure. However, NIV is still underutilized at many medical centers. The purposes of this project will be to acquire information related to NIV use, to identify reasons for underutilization, to implement interventions that encourage more appropriate use of NIV, and to evaluate the effectiveness of the interventions. Reliable information on NIV use as well as analysis of reasons for underutilization will provide insight into ways of enhancing NIV use. We will determine utilization rate, technology used, patient diagnoses, duration of ventilator use and hospital stay, and success rates as recorded on case report forms (CRFs). After completing the survey, we will provide an educational program to randomly selected institutions (one-half of the total) aimed at increasing the knowledge and skill of physicians, nurses, and therapists regarding use and implementation of NIV. Data will be gathered for a second round with the same data-gathering instruments used during
| Condition |
|---|
|
COPD Congestive Heart Failure Asthma Respiratory Distress Syndrome, Adult Pneumonia |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | Enhancing Utilization of Non-Invasive Positive Pressure Ventilation in Critical Care |
| Estimated Enrollment: | 800 |
| Study Start Date: | November 2003 |
| Estimated Study Completion Date: | December 2012 |
Show Detailed Description
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Patients 18 years of age or older who require mechanical ventilation.
Inclusion Criteria:
- Starting on mechanical ventilation (including: invasive, noninvasive, CPAP or BiPAP for purpose of treatment of respiratory failure)
- 18 years of age or older
Exclusion Criteria:
- Use of home mechanical ventilation, including nocturnal ventilation, continuous mechanical ventilation,BiPAP.
- Continuous use of CPAP or BiPAP for treatment of obstructive sleep apnea.
- Placed on mechanical ventilation for purposes of surgical anesthesia or use of anesthesia for a diagnostic procedure.
- Patient has tracheostomy or was intubated endotracheally prior to admission.
Contacts and Locations| United States, Massachusetts | |
| Tufts Medical Center | |
| Boston, Massachusetts, United States, 02111 | |
| Principal Investigator: | Nicholas S. Hill, MD | Tufts Medical Center |
More Information
Additional Information:
No publications provided
| Responsible Party: | Tufts Medical Center |
| ClinicalTrials.gov Identifier: | NCT00458926 History of Changes |
| Other Study ID Numbers: | 6742 |
| Study First Received: | April 9, 2007 |
| Last Updated: | May 30, 2012 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by Tufts Medical Center:
|
ventilation, mechanical intubation, endotracheal respiratory insufficiency |
Additional relevant MeSH terms:
|
Asthma Heart Failure Pneumonia Respiratory Distress Syndrome, Newborn Respiratory Distress Syndrome, Adult Acute Lung Injury Bronchial Diseases Respiratory Tract Diseases Lung Diseases, Obstructive Lung Diseases Respiratory Hypersensitivity |
Hypersensitivity, Immediate Hypersensitivity Immune System Diseases Heart Diseases Cardiovascular Diseases Respiratory Tract Infections Respiration Disorders Infant, Premature, Diseases Infant, Newborn, Diseases Lung Injury |
ClinicalTrials.gov processed this record on May 16, 2013