Non-Invasive Diagnostic and Functional Evaluation of Cardiac Involvement in Patients With Systemic Sclerosis
Recruitment status was Recruiting
The aim of this study was to assess serum N-terminal proBNP (NT-proBNP) in systemic sclerosis patients and to establish whether it reflects the severity of RV overload.
|Study Design:||Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
|Study Start Date:||April 2006|
|Estimated Study Completion Date:||April 2010|
Elevated serum brain natriuretic peptide (BNP) levels released from myocytes of ventricles upon stretch have been found in patients with isolated right ventricular (RV) pressure overload. However, limited data suggest that serum BNP may be elevated in patients with systemic sclerosis (SSc), especially with RV dysfunction. The aim of this study was to assess serum N-terminal proBNP (NT-proBNP) in SSc patients and to establish whether it reflects the severity of RV overload.
|Contact: Ciurzyński Michał, M.D, Ph.D||+48 22 502 11 email@example.com|
|Contact: Piotr Pruszczyk, M.D, Ph.D.||+48 22 501 11 firstname.lastname@example.org|
|Warsaw, Lindleya 4, Poland, 02-005|
|Contact: Michał Ciurzyński, M.D, Ph.D +48 22 502 11 44 email@example.com|
|Principal Investigator:||Michał Ciurzyński, M.D., Ph.D||Medical University of Warsaw|