Pilot Study of Human Tear Proteins

This study has been terminated.
(Stopped due to low enrollment)
Sponsor:
Information provided by (Responsible Party):
University of Colorado, Denver
ClinicalTrials.gov Identifier:
NCT00453258
First received: March 26, 2007
Last updated: January 15, 2013
Last verified: October 2012
  Purpose

The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film from diseased and non-diseased patients. This pilot study will provide data to plan prospective research to better delineate the utility of tear proteins in diagnosing and following disease status in a non-invasive fashion.


Condition Intervention
Eye Disease
Other: Eye Examination

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Analysis of Human Tear Proteins: A Pilot Study to Describe the Tear Film Proteome of Patients Undergoing Ophthalmic Examination.

Resource links provided by NLM:


Further study details as provided by University of Colorado, Denver:

Primary Outcome Measures:
  • Plan Prospective Research [ Time Frame: Throughout study participation ] [ Designated as safety issue: No ]
    Pilot study will provide data to plan prospective research to better delineate the utility of tear proteins in diagnosing and following disease status in a non-invasive fashion.


Enrollment: 63
Study Start Date: February 2007
Study Completion Date: September 2011
Primary Completion Date: September 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Study Subject
Subjects receiving eye examination
Other: Eye Examination
Subjects receiving eye examination

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Subjects receiving eye examination

Criteria

Inclusion Criteria:

  • 18 years of age and older
  • able to cooperate with tear sample collection
  • provide written informed consent

Exclusion Criteria:

  • special populations (children, pregnant or lactating females, prisoners, etc)
  • refusal to sign sudy consent
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00453258

Locations
United States, Colorado
Rocky Mountain Lions Eye Institute
Aurora, Colorado, United States, 80045
Sponsors and Collaborators
University of Colorado, Denver
Investigators
Principal Investigator: Malik Y. Kahook, MD Rocky Mountain Lions Eye Institute
  More Information

No publications provided

Responsible Party: University of Colorado, Denver
ClinicalTrials.gov Identifier: NCT00453258     History of Changes
Other Study ID Numbers: 06-0862
Study First Received: March 26, 2007
Last Updated: January 15, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by University of Colorado, Denver:
ocular proteomics
eye disease
proteomics

Additional relevant MeSH terms:
Eye Diseases

ClinicalTrials.gov processed this record on April 17, 2014