Comparison of Autologous Serum and Umbilical Cord Serum Eyedrops for Dry Eye Syndrome
To compare the therapeutic effect between autologous serum and umbilical cord serum eyedrops in the treatment of severe dry eye syndrome.
Dry Eye Syndrome
Drug: Umbilical cord serum eyedrops
Drug: Autologous serum eyedrops
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Official Title:||Comparison of Autologous Serum and Umbilical Cord Serum Eyedrops for Dry Eye Syndrome|
Ninety-two eyes of 48 patients with severe dry eye syndrome (34 eyes of 17 patients with Sjögren’s syndrome and 58 eyes of 31 patients with non-Sjögren’s syndrome) were treated with either 20% autologous serum (41 eyes of 21 patients) or umbilical cord serum eyedrops (51 eyes of 27 patients). Symptom scoring, corneal sensitivity test, tear film break-up time (BUT), Schirmer test, tear clearance rate (TCR), corneal fluorescein staining, and conjunctival impression cytology were performed before and 1 month and 2 months after treatment.
|Korea, Republic of|
|Chonnam national university hospital|
|Gwangju, Korea, Republic of, 501-220|
|Study Director:||Kyung chul Yoon, M.D.||Chonnam natianl university hospital|