Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest
The recruitment status of this study is unknown because the information has not been verified recently.
Verified February 2009 by Radboud University.
Recruitment status was Recruiting
Information provided by:
First received: February 28, 2007
Last updated: February 5, 2009
Last verified: February 2009
Survivors of a cardiac arrest frequently develop severe postanoxic encephalopathy. Derangements in cerebral blood after return of spontaneous circulation play an important role in the pathogenesis of postanoxic encephalopathy. In the present study we examine the effect of mild therapeutic hypothermia on cerebral blood flow and carbondioxide reactivity in patients after cardiac arrest.
||Observational Model: Cohort
Time Perspective: Prospective
||Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest
| Estimated Enrollment:
| Study Start Date:
|Ages Eligible for Study:
||18 Years to 95 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Patients after cardiac arrest, comatose and treated with therapeutic hypothermia
- adult patients
- GCS after return of circulation < 7
- Induced mild hypothermia for 24 hours
- primary rhythm ventricular fibrillation
- Cardiogenic shock with expected survival < 24 hrs
- No informed consent
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00441753
|Radboud University Nijmegen Medical Centre
|Nijmegen, Netherlands, 6500 HB |
|Contact: Cornelia Hoedemaekers, MD PhD 00.31.24.3617273 C.Hoedemaekers@ic.umcn.nl |
|Sub-Investigator: Koen Simons, MD |
||Cornelia Hoedemaekers, MD PhD
||Johannes van der Hoeven, MD PhD
No publications provided
||Radboud UNiversity Nijmegen Medical Centre
History of Changes
|Other Study ID Numbers:
|Study First Received:
||February 28, 2007
||February 5, 2009
||Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on July 23, 2014
Central Nervous System Diseases
Nervous System Diseases
Body Temperature Changes
Signs and Symptoms