Comparison of Ultrasonic Pachymetry With Orbscan in Corneal Haze - Full Text View

Sponsor:	Baskent University
Information provided by:	Baskent University
ClinicalTrials.gov Identifier:	NCT00439114

Purpose

This study is planned to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. Corneal haze is graded with slit-lamp by a single examiner. Ultrasonic and Orbscan II pachymetry measurements are obtained. Paired t and Kruskal-Wallis tests are used to evaluate the difference between ultrasonic and Orbscan pachymetry measurements. Correlation of the two methods and haze grade is determined with Kendall’s tau-b correlation analysis.

Condition
Corneal Opacity

Study Type:	Observational
Study Design:	Observational Model: Defined Population Primary Purpose: Screening Time Perspective: Cross-Sectional Time Perspective: Prospective
Official Title:	Comparison of Ultrasonic Pachymetry With Orbscan in Corneal Haze

Further study details as provided by Baskent University:

Estimated Enrollment:	40
Study Start Date:	July 2005
Estimated Study Completion Date:	June 2006

Detailed Description:

We planned this study to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. In this institutional based, prospective, controlled clinical trial subjects with corneal haze not related to surgery are included. Normal eyes are used as control group to calculate the customized acoustic factor. Corneal haze is graded with slit-lamp by a single examiner. Ultrasonic and Orbscan II pachymetry measurements are obtained by one technician each masked to the other measurement. Paired t and Kruskal-Wallis tests are used to evaluate the difference between ultrasonic and Orbscan pachymetry measurements. Correlation of the two methods and haze grade is determined with Kendall’s tau-b correlation analysis. According to the results of the study, we will determine which method is accurate in subjects with corneal haze.

Eligibility

Ages Eligible for Study:	18 Years to 71 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Patients with significant corneal haze on slit-lamp are included in the study group. 50 eyes of 50 age-matched patients with normal eye and clear cornea are included in the control group. Only one eye of each subject is included.

Exclusion Criteria:

Exclusion criteria to participate in the study are previous ocular surgery, history of contact lens use, glaucoma, and topical ocular medication use, excluding artificial tears.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00439114

Locations

Turkey
Baskent University, Faculty of Medicine, Adana Hospital
Adana, N.a., Turkey, 01250

Sponsors and Collaborators

Baskent University

Investigators

Principal Investigator:

Rana Altan-Yaycioglu, M.D.

Baskent University, Faculty of Medicine, Department of Ophthalmology

More Information

Publications:

Boscia F, La Tegola MG, Alessio G, Sborgia C. Accuracy of Orbscan optical pachymetry in corneas with haze. J Cataract Refract Surg. 2002 Feb;28(2):253-8.

Iskander NG, Anderson Penno E, Peters NT, Gimbel HV, Ferensowicz M. Accuracy of Orbscan pachymetry measurements and DHG ultrasound pachymetry in primary laser in situ keratomileusis and LASIK enhancement procedures. J Cataract Refract Surg. 2001 May;27(5):681-5.

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Altan-Yaycioglu R, Pelit A, Akova YA. Comparison of ultrasonic pachymetry with Orbscan in corneal haze. Graefes Arch Clin Exp Ophthalmol. 2007 Dec;245(12):1759-63. Epub 2007 Jun 22.

ClinicalTrials.gov Identifier:	NCT00439114 History of Changes
Other Study ID Numbers:	KA05/207
Study First Received:	February 21, 2007
Last Updated:	February 21, 2007
Health Authority:	Turkey: Ministry of Health

Keywords provided by Baskent University:

Corneal topography, corneal opacity, keratitis, trachoma

Additional relevant MeSH terms:

Corneal Opacity
Corneal Diseases
Eye Diseases

ClinicalTrials.gov processed this record on February 09, 2012