Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

This study has been completed.
Sponsor:
Information provided by:
Hospital do Cancer, Sao Paulo
ClinicalTrials.gov Identifier:
NCT00432718
First received: February 7, 2007
Last updated: NA
Last verified: February 2007
History: No changes posted
  Purpose

Compare the incidence of ventilator associated pneumonia with or without tracheal isotonic saline instillation before tracheal suctioning


Condition Intervention
Mechanical Ventilation
Critically Ill Patients
Procedure: Saline Instillation before Tracheal Suctioning

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Single Blind
Primary Purpose: Prevention

Resource links provided by NLM:


Further study details as provided by Hospital do Cancer, Sao Paulo:

Primary Outcome Measures:
  • incidence of ventilator associated pneumonia

Secondary Outcome Measures:
  • atelectasis
  • tube occlusion

Estimated Enrollment: 260
Study Start Date: August 2001
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Consecutive patients foreseen to receive mechanical ventilation for more than 72 hours

Exclusion Criteria:

  • Previous mechanical ventilation in the last month
  • Mechanical ventilation for more than 6 hours before arrival at ICU,
  • Contraindication to bronchoscopy and
  • Be expected to die or undergo withdrawal treatment within 48 hours-
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00432718

Locations
Brazil
ICU Hospital do Câncer
Sao Paulo, SP, Brazil, 01509-010
Sponsors and Collaborators
Hospital do Cancer, Sao Paulo
Investigators
Principal Investigator: Pedro Caruso, MD Intensive Care Unit - Hospital do Câncer and University of Sao Paulo Medical School
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00432718     History of Changes
Other Study ID Numbers: 342/01
Study First Received: February 7, 2007
Last Updated: February 7, 2007
Health Authority: Brazil: National Committee of Ethics in Research

Keywords provided by Hospital do Cancer, Sao Paulo:
Pneumonia
Ventilator Associated Pneumonia
Prevention

Additional relevant MeSH terms:
Critical Illness
Pneumonia, Ventilator-Associated
Disease Attributes
Pathologic Processes
Cross Infection
Infection
Ventilator-Induced Lung Injury
Lung Injury
Lung Diseases
Respiratory Tract Diseases
Pneumonia
Respiratory Tract Infections

ClinicalTrials.gov processed this record on October 01, 2014