Text Size

Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

This study has been completed.
Sponsor:
Information provided by:
Hospital do Cancer, Sao Paulo
ClinicalTrials.gov Identifier:
NCT00432718
First received: February 7, 2007
Last updated: NA
Last verified: February 2007
History: No changes posted
  Purpose

Compare the incidence of ventilator associated pneumonia with or without tracheal isotonic saline instillation before tracheal suctioning


Condition Intervention
Mechanical Ventilation
Critically Ill Patients
 Procedure: Saline Instillation before Tracheal Suctioning

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Single Blind
Primary Purpose: Prevention

Resource links provided by NLM:

MedlinePlus related topics: Pneumonia
U.S. FDA Resources

Further study details as provided by Hospital do Cancer, Sao Paulo:

Primary Outcome Measures:
  • incidence of ventilator associated pneumonia

Secondary Outcome Measures:
  • atelectasis
  • tube occlusion

Estimated Enrollment: 260
Study Start Date: August 2001
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Consecutive patients foreseen to receive mechanical ventilation for more than 72 hours

Exclusion Criteria:

  • Previous mechanical ventilation in the last month
  • Mechanical ventilation for more than 6 hours before arrival at ICU,
  • Contraindication to bronchoscopy and
  • Be expected to die or undergo withdrawal treatment within 48 hours-
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00432718

Locations
Brazil
ICU Hospital do Câncer
Sao Paulo, SP, Brazil, 01509-010
Sponsors and Collaborators
Hospital do Cancer, Sao Paulo
Investigators
Principal Investigator: Pedro Caruso, MD Intensive Care Unit - Hospital do Câncer and University of Sao Paulo Medical School
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00432718     History of Changes
Other Study ID Numbers: 342/01
Study First Received: February 7, 2007
Last Updated: February 7, 2007
Health Authority: Brazil: National Committee of Ethics in Research

Keywords provided by Hospital do Cancer, Sao Paulo:
Pneumonia
Ventilator Associated Pneumonia
Prevention

Additional relevant MeSH terms:
Critical Illness
Pneumonia
Pneumonia, Ventilator-Associated
Disease Attributes
Pathologic Processes
Lung Diseases
 Respiratory Tract Diseases
Respiratory Tract Infections
Cross Infection
Infection
Ventilator-Induced Lung Injury
Lung Injury

ClinicalTrials.gov processed this record on May 23, 2013