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Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards

The recruitment status of this study is unknown because the information has not been verified recently.
Verified October 2007 by Ludwig-Maximilians - University of Munich.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Ludwig-Maximilians - University of Munich
ClinicalTrials.gov Identifier:
NCT00431483
First received: February 1, 2007
Last updated: November 1, 2007
Last verified: October 2007
History of Changes
  Purpose

The purpose of this study is to establish the impact of a pharmacist's recommendations regarding choice, dosing and duration of antibiotic therapy on quality and cost of antibiotic treatment on surgical wards.


Condition Intervention
Bacterial Infections
 Behavioral: pharmaceutical consulting

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Supportive Care
Official Title: Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Ludwig-Maximilians - University of Munich:

Primary Outcome Measures:
  • overall expenditure for antibiotics during study period [ Time Frame: October 2008 ]
  • number of inappropriately prescribed antibiotics [ Time Frame: October 2008 ]

Estimated Enrollment: 600
Study Start Date: February 2007
Estimated Study Completion Date: March 2008
Intervention Details:
    Behavioral: pharmaceutical consulting
    to measure if information and advice by a pharmacist has an impact on quality and quantity of prescribed antibacterials
Detailed Description:

Inappropriate or incorrect use of antibacterials exerts selection pressure on pathogens potentiating emergence of resistance, puts patients at risk for unnecessary adverse drug reactions and potentially prolongs the length of stay in hospital thus increasing healthcare costs.

In an effort to improve the quality of antibiotic drug therapy on surgical wards of a large university hospital, specific consulting by a clinical pharmacist was established.

The objective of this study is to assess the impact of pharmaceutical consulting on the quality and costs of antibiotic use in surgical wards.

Comparison:

Within a control period the current pattern of antibiotic use is monitored. During the intervention period, the impact of the interventions made by the clinical pharmacist on antibiotic use is examined. One ward serves as a parallel control group; no intervention is being made on this ward throughout this study.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • female and male patients receiving antibiotics for a proven or suspected infection on designated surgical wards

Exclusion Criteria:

  • patients under 18
  • patients unable or unwilling to consent to their data being evaluated
  • patients receiving antibiotics perioperatively as prophylaxis
  • patients receiving antibiotics for less than 48hrs
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00431483

Contacts
Contact: Alexandra Weber, M Pharm +49-89-7095-2467 alexandra.weber@med.uni-muenchen.de

Locations
Germany
Luwig Maximilians University - Klinikum Grosshadern Recruiting
Munich, Bavaria, Germany, 81377
Contact: Alexandra Weber, MPharm     089-7095 ext 2467     alexandra.weber@med.uni-muenchen.de    
Sponsors and Collaborators
Ludwig-Maximilians - University of Munich
Investigators
Study Director: Karl-Walter Jauch, Prof. Dr. Klinikum Grosshadern
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00431483     History of Changes
Other Study ID Numbers: AW2007
Study First Received: February 1, 2007
Last Updated: November 1, 2007
Health Authority: Germany: Ethics Commission

Keywords provided by Ludwig-Maximilians - University of Munich:
antibacterial agents
surgery
pharmacist
economics, pharmaceutical

Additional relevant MeSH terms:
Bacterial Infections
Anti-Bacterial Agents
Anti-Infective Agents
Therapeutic Uses
Pharmacologic Actions

ClinicalTrials.gov processed this record on May 19, 2013