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Long-Term IOP Fluctuation and VF Progression After Triple Procedure

This study has been completed.
Sponsor:
Information provided by:
Yonsei University
ClinicalTrials.gov Identifier:
NCT00428740
First received: January 29, 2007
Last updated: NA
Last verified: January 2007
History: No changes posted
  Purpose

Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for patients with coexisting glaucoma and visually significant cataracts.


Condition
Glaucoma
Filtering Surgery
Intraocular Pressure

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Retrospective
Official Title: Long-Term Intraocular Pressure Fluctuation and Visual Field Progression in Glaucoma Patients With Low Intraocular Pressure After Triple Procedure

Resource links provided by NLM:

MedlinePlus related topics: Glaucoma
U.S. FDA Resources

Further study details as provided by Yonsei University:

Estimated Enrollment: 300
Study Start Date: October 2005
Estimated Study Completion Date: December 2005
Detailed Description:

Previous studies reported that lowering intraocular pressure (IOP) slowed the advancement of visual field damage in glaucoma patients. However, even if the IOP can been substantially lowered, reduction of mean and peak IOP does not always prevent visual field progression.We believe that the long-term IOP fluctuation may play a significant role in visual field deterioration in those patients.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  1. Underwent triple procedure
  2. At leas 3 years of follow-up after surgery
  3. IOP <18mmHg at each postoperative visit
  4. A minimum of 5 visual field examinations
  5. A reference visual field defect score of 16 or less
  6. Good reliability indices of visual field

Exclusion Criteria:

  1. Any other significant ocular diseases or intraocular surgical histories,
  2. Diseases that may affect visual field or diabetes
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00428740

Locations
Korea, Republic of
Yonsei University College of Medicine
Seoul, Korea, Republic of, 135-720
Sponsors and Collaborators
Yonsei University
Investigators
Principal Investigator: Gong Je Seong, MD, PhD Yondgong Severance Hospital, Yonsei University College of Medicine
  More Information

No publications provided by Yonsei University

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

ClinicalTrials.gov Identifier: NCT00428740     History of Changes
Other Study ID Numbers: 3-2006-0388
Study First Received: January 29, 2007
Last Updated: January 29, 2007
Health Authority: South Korea: Institutional Review Board

Additional relevant MeSH terms:
Glaucoma
Ocular Hypertension
Eye Diseases

ClinicalTrials.gov processed this record on June 18, 2013