Heredity of Retinal Vessel Tortuosity
The purpose of this study is to asses the relative influence of genetic and environmental influence on the tortuosity of retinal arterioles in eyes of 218 healthy Danish twins aged 20-46 years. We expect to find a high heredity for the variation in tortuosity. This knowledge can contribute to the elucidation of the pathology in retinal diseases.
Retinopathy of Prematurity
|Study Design:||Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Prospective
|Official Title:||Heredity of Retinal Vessel Tortuosity - A Twin Study|
|Study Start Date:||January 1998|
|Estimated Study Completion Date:||December 1998|
All persons underwent an ophthalmic examination including refraction, slit lamp biomicroscopy and digital fundus photography. Two independent graders (both with an MD degree) made a visual grading of the severity of tortuosity of the retinal arterioles in the fundus images.
|Department of Ophthalmology Glostrup Hospital|
|Glostrup, Copenhagen County, Denmark, DK-2600|
|Principal Investigator:||Michael Larsen, Prof. MD||Department of Ophthalmology Glostrup Hospital University of Copenhagen|