A Randomised Controlled Trial of Face Masks and Hand Hygiene in Reducing Influenza Transmission in Households

This study has been completed.
Sponsor:
Collaborator:
The University of Hong Kong
Information provided by:
Centers for Disease Control and Prevention
ClinicalTrials.gov Identifier:
NCT00425893
First received: January 19, 2007
Last updated: April 12, 2012
Last verified: April 2012
  Purpose

This study will test the effectiveness of face masks and hand cleaning in preventing the spread of influenza within households


Condition Intervention
Influenza
Behavioral: hand hygiene
Other: health education
Device: face masks

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: A Randomised Controlled Trial of Face Masks and Hand Hygiene in Reducing Influenza Transmission in Households

Resource links provided by NLM:


Further study details as provided by Centers for Disease Control and Prevention:

Primary Outcome Measures:
  • secondary influenza infection [ Time Frame: 7 days ] [ Designated as safety issue: No ]

Enrollment: 6069
Study Start Date: February 2007
Study Completion Date: November 2008
Primary Completion Date: September 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: 1
health education
Other: health education
Proper nutrition, etc.
Experimental: 2
hand hygiene
Behavioral: hand hygiene
alcohol-based hand wash
Experimental: 3
masks and hand hygiene
Behavioral: hand hygiene
alcohol-based hand wash
Device: face masks
face masks

Detailed Description:

Randomised controlled trial of surgical masks and alcohol hand wash among approximately 6069 Hong Kong residents who have a household member diagnosed with influenza. Influenza in index member and secondary infection will be documented with rapid influenza tests and PCR. Minimal risk to participants.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Member of family with influenza infected member

Exclusion Criteria:

  • Age less than 2 yr
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00425893

Locations
China, Hong Kong
University of Hong Kong
Hong Kong, Hong Kong, China
Sponsors and Collaborators
The University of Hong Kong
Investigators
Principal Investigator: Benjamin J Cowling, PhD The University of Hong Kong
  More Information

No publications provided by Centers for Disease Control and Prevention

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Peter Houck, MD, CDC
ClinicalTrials.gov Identifier: NCT00425893     History of Changes
Other Study ID Numbers: CDC-NCCID-UCI000439A, CDC Grant# 1 U01 CI000439-01
Study First Received: January 19, 2007
Last Updated: April 12, 2012
Health Authority: Hong Kong: Joint CUHK-NTEC Clinical Research Ethics Committee
United States: Federal Government

Keywords provided by Centers for Disease Control and Prevention:
influenza
masks
transmission
hand hygiene
non-pharmacologic interventions

Additional relevant MeSH terms:
Influenza, Human
Orthomyxoviridae Infections
RNA Virus Infections
Virus Diseases
Respiratory Tract Infections
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on April 17, 2014