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Mechanism and Prevention of Remote Organ Injury Following Ruptured Aortic Aneurysm

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2006 by University Health Network, Toronto.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
The Physicians' Services Incorporated Foundation
Information provided by:
University Health Network, Toronto
ClinicalTrials.gov Identifier:
NCT00416000
First received: December 22, 2006
Last updated: December 26, 2006
Last verified: December 2006
History of Changes
  Purpose

It has been estimated that 80% of deaths from abdominal aortic aneurysms results from rupture. Endovascular Aneurysm Repair (EVAR) has been applied to RAAA (Ruptured Abdominal Aortic Aneurysm) patients with reports of improvements. Despite the use of EVAR, patients have developed complications with lung and kidney function. This study will investigate certain biochemical processes that will potentially reduce these complications. Knowledge gained from this study may also be used to further research in this field through larger studies.


Condition
Abdominal Aortic Aneurysm

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Retrospective/Prospective
Official Title: Phase 1 Study of Complement Activation Following Ruptured Abdominal Aortic Aneurysm: Combining Human Observation With Animal Experimentation to Establish a Framework for Human Therapy

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University Health Network, Toronto:

Estimated Enrollment: 60
Study Start Date: January 2006
  Eligibility

Ages Eligible for Study:   30 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Open/Elective EVAR patients

Exclusion Criteria:

  • Patients who do not present with abdominal aortic aneurysms or ruptured abdominal aortic aneurysm
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00416000

Contacts
Contact: Thomas F Lindsay, MD 416 340 4800 ext 4620 Thomas.Lindsay@uhn.on.ca
Contact: William Johnson 416 581 7498

Locations
Canada, Ontario
Toronto General Hospital Recruiting
Toronto, Ontario, Canada, M5G 2C4
Sponsors and Collaborators
University Health Network, Toronto
The Physicians' Services Incorporated Foundation
Investigators
Principal Investigator: Thomas F Lindsay, MD TGH, UHN
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00416000     History of Changes
Other Study ID Numbers: 06-0671B
Study First Received: December 22, 2006
Last Updated: December 26, 2006
Health Authority: Canada: Health Canada

Keywords provided by University Health Network, Toronto:
Open/Elective EVAR patients

Additional relevant MeSH terms:
Aneurysm
Aortic Aneurysm
Aortic Aneurysm, Abdominal
Aortic Rupture
Vascular Diseases
 Cardiovascular Diseases
Aortic Diseases
Aneurysm, Ruptured
Rupture
Wounds and Injuries

ClinicalTrials.gov processed this record on June 18, 2013