Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment
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Purpose
The purpose of this study is to determine the extend and the nature of anemia in school children and the correlation between anemia and schistosomiasis infections, malaria infections and/or malnutrition (iron deficiency).
| Condition | Intervention |
|---|---|
|
Anaemia Schistosomiasis Infection Malaria Iron Deficiency |
Drug: praziquantl, iron, ACT |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment |
- hemoglobin level
- Schistosomiasis infection
- malaria infection
- iron deficiency
| Enrollment: | 1500 |
| Study Start Date: | July 2006 |
| Study Completion Date: | January 2010 |
| Primary Completion Date: | January 2010 (Final data collection date for primary outcome measure) |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
children 9-12 years of age
Children with schistosomiasis, malaria and anaemia
|
Drug: praziquantl, iron, ACT |
Detailed Description:
The study will be carried out in an area around Lake Victoria in Kenya where the prevalence of schistosomiasis and malaria are highest in the areas nearest to the Lake. Depending on the prevalence of schistosomiasis a sample of between 876 to 2.524 children will be enrolled in the study. The children who will be in the age between 9 to 12 year, will have their stool and urine examined for schistosomiasis and intestinal worms and a blood sample will be examined for malaria parasites and the hemoglobin level. Children will also be weight, measured and examined by a doctor and register their food intake over one week, to determine their nutritional status. Children who are found to be infected with schistosomiasis, intestinal worms or malaria will be offered treatment. Children who are found to have anemia will be offered a course of iron supplementation, children with severe anemia will be referred to the nearest health facility for treatment. 12 months after the initial examinations and treatment all children will have a re-examination of their stool, urine and blood.
Eligibility| Ages Eligible for Study: | 9 Years to 12 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
children 9-12 years of age
Inclusion Criteria:
- school children between 9 to 12 year
Contacts and Locations| Kenya | |
| Kenya Medical Research Institute | |
| Kisumu, Kenya | |
| Principal Investigator: | Diana Karanja, DR | Kenya Medical Research Institute |
More Information
No publications provided
| ClinicalTrials.gov Identifier: | NCT00414479 History of Changes |
| Other Study ID Numbers: | SRP-KY-DK-06 |
| Study First Received: | December 20, 2006 |
| Last Updated: | January 13, 2010 |
| Health Authority: | Kenya: Ministry of Health |
Keywords provided by DBL -Institute for Health Research and Development:
|
schistosomiasis anaemia malaria iron deficiency |
Additional relevant MeSH terms:
|
Anemia Malaria Schistosomiasis Anemia, Iron-Deficiency Hematologic Diseases Protozoan Infections |
Parasitic Diseases Trematode Infections Helminthiasis Anemia, Hypochromic Iron Metabolism Disorders Metabolic Diseases |
ClinicalTrials.gov processed this record on May 16, 2013