Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer
RATIONALE: Learning about the long-term effects of chemotherapy and radiation therapy on brain function may help doctors plan cancer treatments.
PURPOSE: This clinical trial is looking at the neurological effects of chemotherapy and radiation therapy in patients with colon cancer.
Long-term Effects Secondary to Cancer Therapy in Adults
Procedure: cognitive assessment
Procedure: magnetic resonance imaging
Procedure: management of therapy complications
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Neurological Effects of Chemotherapy and Radiation Treatment: Colon Cancer|
- Nature and long-term ramifications of CNS injury as a result of cancer treatment
- Differences in cognitive measures and MRI data
- Relationship between MRI measures and cognitive performance
|Study Start Date:||April 2003|
|Study Completion Date:||August 2006|
|Primary Completion Date:||August 2006 (Final data collection date for primary outcome measure)|
- Identify the nature and long-term ramifications of CNS injury as a result of cancer treatment in patients with colon cancer.
- Analyze differences in cognitive measures and MRI data in these patients.
- Correlate MRI measures with cognitive performance in these patients.
OUTLINE: Patients undergo cognitive performance assessment and MRI.
PROJECTED ACCRUAL: A total of 42 patients will be accrued for this study.
|United States, Arizona|
|Arizona Cancer Center at University of Arizona Health Sciences Center|
|Tucson, Arizona, United States, 85724-5024|
|Study Chair:||Sheryl Reminger, MD||University of Arizona|