Trial of Adaptive 18F-FDG-PET Biological Intensity-modulated Radiotherapy (BG-IMRT) in Patients With Head and Neck Tumor

This study has been completed.
Information provided by:
University Hospital, Ghent Identifier:
First received: November 30, 2006
Last updated: September 3, 2010
Last verified: September 2010

This study will evaluate the feasibility of higher and prolonged dose escalation concentrated in the intra-tumoral regions which are FDG-avid after two weeks of radiotherapy.

Condition Intervention Phase
Head and Neck Tumor
Procedure: 18F-FDG-PET radiotherapy
Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Phase I Trial of Adaptive 18F-FDG-PET Biological Intensity-modulated Radiotherapy (BG-IMRT) With Patients With Head and Neck Tumor

Resource links provided by NLM:

Further study details as provided by University Hospital, Ghent:

Primary Outcome Measures:
  • Tumor recurrences

Estimated Enrollment: 24
Study Start Date: November 2006
Study Completion Date: February 2010
Primary Completion Date: August 2009 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Head and neck tumor
  • Aged > 18 years
  Contacts and Locations
Please refer to this study by its identifier: NCT00406289

University Hospital Ghent
Ghent, Belgium, 9000
Sponsors and Collaborators
University Hospital, Ghent
Principal Investigator: Wilfried De Neve, MD, PhD University Hospital, Ghent
  More Information

Additional Information:
No publications provided

Responsible Party: Wilfried De Neve, University Hospital Ghent Identifier: NCT00406289     History of Changes
Other Study ID Numbers: 2006/391
Study First Received: November 30, 2006
Last Updated: September 3, 2010
Health Authority: Belgium: Institutional Review Board

Additional relevant MeSH terms:
Head and Neck Neoplasms
Neoplasms by Site
Neoplasms processed this record on April 17, 2014