The Role of Steroids Following Selective Laser Trabeculoplasty

This study has been completed.
Sponsor:
Information provided by:
West Virginia University
ClinicalTrials.gov Identifier:
NCT00406042
First received: November 29, 2006
Last updated: March 28, 2007
Last verified: March 2007
  Purpose

To evaluate whether or not using topical steroids after selective laser trabeculoplasty affects intraocular pressure outcomes.


Condition Intervention
Glaucoma
Drug: prednisolone acetate 1%

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment
Official Title: The Role of Topical Prednisolone Acetate Following Selective Laser Trabeculoplasty

Resource links provided by NLM:


Further study details as provided by West Virginia University:

Primary Outcome Measures:
  • Intraocular pressure reduction

Secondary Outcome Measures:
  • Anterior chamber inflammation

Estimated Enrollment: 25
Study Start Date: September 2005
Study Completion Date: June 2006
Detailed Description:

Subjects undergoing bilateral SLT will be randomly assigned to use prednisolone acetate 1% in one eye four times daily with no treatment in the fellow eye, for one week following SLT. Examinations will occur at baseline, and one week, one month and three months after SLT. IOP and anterior chamber inflammation will be noted at each visit.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • glaucoma or ocular hypertension
  • need for bilateral SLT

Exclusion Criteria:

  • eye disease precluding accurate IOP measurement
  • contraindication to topical prednisolone acetate
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00406042

Locations
United States, West Virginia
West Virginia University Eye Institute
Morgantown, West Virginia, United States, 26505
Sponsors and Collaborators
West Virginia University
Investigators
Principal Investigator: Tony Realini, MD West Virginia University Eye Institute
  More Information

No publications provided by West Virginia University

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00406042     History of Changes
Other Study ID Numbers: 16678
Study First Received: November 29, 2006
Last Updated: March 28, 2007
Health Authority: United States: Institutional Review Board

Keywords provided by West Virginia University:
glaucoma
trabeculoplasty
steroids

Additional relevant MeSH terms:
Glaucoma
Ocular Hypertension
Eye Diseases
Methylprednisolone acetate
Prednisolone acetate
Prednisolone
Methylprednisolone
Methylprednisolone Hemisuccinate
Prednisolone hemisuccinate
Prednisolone phosphate
Anti-Inflammatory Agents
Therapeutic Uses
Pharmacologic Actions
Glucocorticoids
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Antineoplastic Agents, Hormonal
Antineoplastic Agents
Antiemetics
Autonomic Agents
Peripheral Nervous System Agents
Central Nervous System Agents
Gastrointestinal Agents
Neuroprotective Agents
Protective Agents

ClinicalTrials.gov processed this record on July 22, 2014